FGFR3 - fibroblast growth factor receptor 3 Gene

Macaca mulatta

Gene ID: 712829 | Gene type: protein coding

About FGFR3

Primary_assembly 5: 1,850,684-1,864,251 forward strand.Mmul_10:CM014340.1

This gene has 2 transcripts (splice variants), 191 orthologues and 53 paralogues.

mRNA	Protein	Name
XM_015137851.2	XP_014993337.1	fibroblast growth factor receptor 3 isoform X11
XM_015137844.2	XP_014993330.1	fibroblast growth factor receptor 3 isoform X2
XM_028848225.1	XP_028704058.1	fibroblast growth factor receptor 3 isoform X12
XM_015137843.2	XP_014993329.1	fibroblast growth factor receptor 3 isoform X1
XM_001101108.4	XP_001101108.1	fibroblast growth factor receptor 3 isoform X10
XM_015137847.2	XP_014993333.1	fibroblast growth factor receptor 3 isoform X4
XM_015137848.2	XP_014993334.1	fibroblast growth factor receptor 3 isoform X5
XM_002802167.3	XP_002802213.1	fibroblast growth factor receptor 3 isoform X6
XM_015137850.2	XP_014993336.1	fibroblast growth factor receptor 3 isoform X8
XM_015137846.2	XP_014993332.1	fibroblast growth factor receptor 3 isoform X3
XM_028848223.1	XP_028704056.1	fibroblast growth factor receptor 3 isoform X7
XM_028848224.1	XP_028704057.1	fibroblast growth factor receptor 3 isoform X9

IgI_2_FGFR

IgI_3_FGFR

PKc_like

Protein Preferred Names

Protein Names

fibroblast growth factor receptor 3

Cat. No.	Product Name	Accession	Purity
HY-P76341	FGFR-3 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)	F7FZR9/XP_001101108.1 (E23-G375)	≥95%
HY-P76342	FGFR-3 Protein, Cynomolgus/Rhesus Macaque (HEK293, His)	F7FZR9/XP_001101108.1 (E23-G375)	≥95%

Approval

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10981	Lenvatinib	Inhibitor	99.75%	Yes
HY-50904	Nintedanib	Inhibitor	99.94%	Yes
HY-18708	Erdafitinib	Inhibitor	99.66%	Unkown
HY-13311	Infigratinib	Inhibitor	99.72%	Yes
HY-109099	Pemigatinib	Inhibitor	99.84%	Yes
HY-100818	Futibatinib	Inhibitor	99.65%	Unkown
HY-11106	Nintedanib esylate	Inhibitor	99.95%	Yes
HY-10981A	Lenvatinib mesylate	Inhibitor	99.86%	Yes
HY-13311A	Infigratinib phosphate	Inhibitor	99.74%	Yes

Clinical Phase

Bioactive Molecules (16)

Cat. No.	Product Name	Effect	Purity	Phase
HY-13330	Fexagratinib	Inhibitor	99.85%	Phase 3
HY-50905	Dovitinib	Inhibitor	99.88%	Phase 3
HY-100019	Rogaratinib	Inhibitor	99.86%	Phase 3
HY-10207	Dovitinib lactate	Inhibitor	99.75%	Phase 3
HY-B0062	Dovitinib lactate hydrate	Inhibitor	/	Phase 3
HY-101568	Roblitinib	Inhibitor	99.74%	Phase 2
HY-13034	Gandotinib	Inhibitor	99.82%	Phase 2
HY-19981	Derazantinib	Inhibitor	99.28%	Phase 2
HY-19957	Zoligratinib	Inhibitor	99.76%	Phase 2
HY-101466A	E7090 succinate	Inhibitor	99.17%	Phase 2
HY-13304	LY2874455	Inhibitor	98.03%	Phase 1
HY-10032	PF 477736	Inhibitor	99.21%	Phase 1
HY-101768	PRN1371	Inhibitor	99.43%	Phase 1
HY-119367	ODM-203	Inhibitor	99.91%	Phase 1
HY-19983	ASP5878	Inhibitor	99.69%	Phase 1
HY-100491	H3B-6527	Inhibitor	≥98.0%	Phase 1

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99384	Vofatamab	Inhibitor	95.00%	Phase 2
HY-P99823	Recifercept		97.10%	Phase 2

Pre-clinical Phase

Bioactive Molecules (29)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12823	BLU9931	Inhibitor	99.97%	Unkown
HY-18602	FIIN-2	Inhibitor	99.32%	Unkown
HY-15599	SSR128129E	Inhibitor	99.85%	Unkown
HY-148779	FGFR3-IN-5	Inhibitor	99.28%	Unkown
HY-145231	FGFR2-IN-2	Inhibitor	98.25%	Unkown
HY-101466	E7090	Inhibitor	99.64%	Unkown
HY-131908	CPL304110	Inhibitor	99.85%	Unkown
HY-15813	FIIN-1	Inhibitor	99.11%	Unkown
HY-18603	FIIN-3	Inhibitor	99.66%	Unkown
HY-P3695	VSPPLTLGQLLS	Inhibitor	98.08%	Unkown
HY-12965	S49076	Inhibitor	99.44%	Unkown
HY-108933	JK-P3	Inhibitor	99.72%	Unkown
HY-148778	FGFR3-IN-4	Inhibitor	/	Unkown
HY-156790	FGFR3-IN-6	Inhibitor	/	Unkown
HY-147714	FGFR3-IN-2	Inhibitor	/	Unkown
HY-151903S	FGFR2/3-IN-1	Inhibitor	/	Unkown
HY-156791	FGFR3-IN-7	Inhibitor	/	Unkown
HY-142921	FGFR-IN-2	Inhibitor	/	Unkown
HY-P3695A	VSPPLTLGQLLS TFA	Inhibitor	/	Unkown
HY-155028	FGFR-IN-11	Inhibitor	/	Unkown
HY-152146	HDAC-IN-50	Inhibitor	/	Unkown
HY-150652	FGFR-IN-8	Inhibitor	/	Unkown
HY-152104	FGFR-IN-9	Inhibitor	/	Unkown
HY-147713	FGFR3-IN-1	Inhibitor	/	Unkown
HY-158248	FGFR4-IN-19	Inhibitor	/	Unkown
HY-147715	FGFR3-IN-3	Inhibitor	/	Unkown
HY-164459	AZ8010	Inhibitor	/	Unkown
HY-159503A	Segigratinib hydrochloride	Inhibitor	/	Unkown
HY-15599A	SSR128129E free acid	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	FGFR3	NCBI	NCBI:2261
Mus musculus	FGFR3	NCBI	NCBI:14184

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