2. Gene
  3. Prx - periaxin Gene

Prx - periaxin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 78960 | Gene type: protein coding

About Prx

Summary

Involved in axon ensheathment and nerve development. Located in myelin sheath. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 3 and Charcot-Marie-Tooth disease type 4F. Orthologous to human PRX (periaxin). [provided by Alliance of Genome Resources, Apr 2022]

Prx Products(1)

mRNA Protein Name
NM_023976.2 NP_076466.2 periaxin
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12591166 RGD
Biological Process GO Annotation Evidence Reference Source
involved in axon ensheathment IEP
IEP: Inferred from expression pattern
8155317 RGD
involved in nerve development IEP
IEP: Inferred from expression pattern
8155317 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

periaxin

Prx Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Prx Q63425 Scn10a Rattus norvegicus Q62968
Anti Bait CoIP
12591166
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Approval
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99554 Topsalysin / Unkown
Clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-14848 Naluzotan 98.05% Phase 3
HY-15472 PRX-08066 Antagonist 97.46% Phase 2
HY-14559 PRX-07034 hydrochloride Antagonist 98.97% Phase 1
HY-100171A PRX933 Agonist / Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99405 Prasinezumab Inhibitor 99.90% Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100171 PRX933 hydrochloride Agonist / Unkown
HY-14848A Naluzotan hydrochloride / Unkown
HY-15472A PRX-08066 maleate Antagonist / Unkown
HY-158198 PRXS571 / Unkown
HY-RS11265 PRX Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-19846 VRX-03011 / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990708 Bizaxofusp / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prx NCBI NCBI:57716
Mus musculus Prx NCBI NCBI:19153