2. Gene
  3. INTS14 - integrator complex subunit 14 Gene

INTS14 - integrator complex subunit 14 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as VWA9; C15orf44

Gene ID: 81556 | Gene type: protein coding

About INTS14

This gene has 18 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in thyroid (RPKM 12.8), testis (RPKM 11.6) and 25 other tissues.

Summary

Predicted to be involved in snRNA 3'-end processing. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

INTS14 Products(10)

mRNA Protein Name
NM_001136043.3 NP_001129515.1 integrator complex subunit 14 isoform 1
NM_001207058.3 NP_001193987.2 integrator complex subunit 14 isoform 4
NM_001207059.3 NP_001193988.2 integrator complex subunit 14 isoform 1
NM_001366360.2 NP_001353289.1 integrator complex subunit 14 isoform 2
NM_001366364.2 NP_001353293.1 integrator complex subunit 14 isoform 1
NM_001366365.2 NP_001353294.1 integrator complex subunit 14 isoform 1
NM_001394794.1 NP_001381723.1 integrator complex subunit 14 isoform 2
NM_001394795.1 NP_001381724.1 integrator complex subunit 14 isoform 3
NM_001394796.1 NP_001381725.1 integrator complex subunit 14 isoform 2
NM_001394797.1 NP_001381726.1 integrator complex subunit 14 isoform 5
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
24981860 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

INTS14 Protein Structure

VWA_2

VWA_2: von Willebrand factor type A domain (3 - 127)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 518 a.a.
Protein Preferred Names Protein Names

integrator complex subunit 14

UPF0464 protein C15orf44

INTS14 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
INTS14 Q96SY0 INTS10 Homo sapiens Q9NVR2
Pull Down
32647223
Intra
INTS14 Q96SY0 INTS10 Homo sapiens Q9NVR2
Anti Tag CoIP
26496610
Intra
INTS14 Q96SY0 INTS13 Homo sapiens Q9NVM9
Anti Tag CoIP
26496610
Intra
INTS14 Q96SY0 INTS13 Homo sapiens Q9NVM9
Pull Down
32647223
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Folic Acid Deficiency Anemia

Folate Deficiency Anaemia

Folic Acid Deficiency Anaemia

Folate Deficiency Anemia

Folate-Deficiency Anaemia

Folate-Deficiency Anemia

Folate-Deficient Megaloblastic Anaemia

Megaloblastic Anemia Due To Folate Deficiency

Anaemia Of Folate Deficiency

Folate Or Folic Acid Deficiency Anaemia Nos

Folic Acid Deficiency Anaemia Nos

Acquired Megaloblastic Anaemia Due To Nutritional Folate Deficiency

Dietary Folic Acid Deficiency Anaemia

Dietary Folate Deficiency Anaemia

Folate Deficiency Anaemia Due To Dietary Causes

Goat'S Milk Anaemia

Acquired Megaloblastic Anaemia Due To Folate Deficiency Secondary To Increased Requirement

Megaloblastic Anaemia Due To Increased Requirements Of Folate

Acquired Megaloblastic Anaemia Due To Folate Deficiency Secondary To Intestinal Disorders

Acquired Megaloblastic Anaemia Due To Decreased Intestinal Absorption Of Folate

Megaloblastic Anaemia Due To Decreased Intestinal Absorption Of Folate
Short-Rib Thoracic Dysplasia 4 With Or Without Polydactyly

Asphyxiating Thoracic Dystrophy 4

SRTD4

Atd4

Jatd

Jeune Asphyxiating Thoracic Dystrophy

Jeune Syndrome 4
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06853 INTS14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus INTS14 VGNC VGNC:30227
Macaca mulatta INTS14 VGNC VGNC:73650
Canis familiaris INTS14 VGNC VGNC:42050
Felis catus INTS14 VGNC VGNC:62942
Rattus norvegicus INTS14 RGD RGD:1359616
Mus musculus INTS14 MGD MGI:1917132