ARPC5L - actin related protein 2/3 complex subunit 5 like Gene

Homo sapiens

Also known as ARC16-2

Gene ID: 81873 | Gene type: protein coding

About ARPC5L

This gene has 3 transcripts (splice variants), 190 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 7.9), testis (RPKM 7.3) and 25 other tissues.

Summary

Predicted to enable actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation and cell migration. Located in extracellular exosome and focal adhesion. [provided by Alliance of Genome Resources, Apr 2022]

ARPC5L Products(1)

mRNA	Protein	Name
NM_030978.3	NP_112240.1	actin-related protein 2月3日 complex subunit 5-like protein

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16169070	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARPC5L Protein Structure

P16-Arc

0
100
153 a.a.

Protein Preferred Names

Protein Names

actin-related protein 2/3 complex subunit 5-like protein

arp2/3 complex 16 kDa subunit 2

ARPC5L Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ARPC5L	Q9BPX5	ARPC4	Homo sapiens	P59998	Anti Tag CoIP	26655834
Intra	ARPC5L	Q9BPX5	ARPC4	Homo sapiens	P59998	Crosslink	30021884
Intra	ARPC5L	Q9BPX5	ARPC4	Homo sapiens	P59998	Y2H Pooling	16169070

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Lissencephaly 3

LIS3	Lissencephaly Due To Tuba1a Mutation
Lissencephaly Type 3	Lissencephaly, Type 3

Leopard Syndrome 1

LPRD1	Noonan Syndrome With Multiple Lentigines 1
Lentiginosis, Cardiomyopathic	Multiple Lentigines Syndrome
Leopard Syndrome, Type 1	Leopard Syndrome
Multiple Lentigines

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01023	ARPC5L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ARPC5L	VGNC	VGNC:38132
Macaca mulatta	ARPC5L	VGNC	VGNC:103242
Mus musculus	ARPC5L	MGD	MGI:1921442
Bos taurus	ARPC5L	VGNC	VGNC:26166
Rattus norvegicus	ARPC5L	RGD	RGD:1308867

Name
Email *

	Sorry, but the email address you supplied was invalid.