2. Gene
  3. Defb1 - defensin beta 1 Gene

Defb1 - defensin beta 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CDK4

Gene ID: 83687 | Gene type: protein coding

About Defb1

Summary

Predicted to enable CCR6 Chemokine Receptor binding activity; double-stranded DNA binding activity; and identical protein binding activity. Involved in acute inflammatory response and response to testosterone. Predicted to be located in microvesicle and sperm midpiece. Predicted to be extrinsic component of membrane. Predicted to be active in extracellular space. Biomarker of obesity and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and lung disease. Orthologous to human DEFB1 (defensin beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Defb1 Products(1)

mRNA Protein Name
NM_031810.2 NP_113998.1 beta-defensin 1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to testosterone IEP
IEP: Inferred from expression pattern
12533413 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-defensin 1

BD-1

rBD-1

Recombinant Defb1 Proteins

Cat. No. Product Name Accession Purity
HY-P7134 BD-1 Protein, Rat O89117 (D33-S69) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W074890 Palmitoylglycine Modulator 99.74% Unkown
HY-RS03678 DEFB1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Defb1 NCBI NCBI:1672