1. Gene
  2. MED10 - mediator complex subunit 10 Gene

MED10 - mediator complex subunit 10 Gene

Homo sapiens

Also known as L6; NUT2; TRG20

Gene ID: 84246 | Gene type: protein coding

About MED10

Cytogenetic location: 5p15.31 Genomic coordinates (GRCh38): 5:6,371,874-6,378,547 (from NCBI)

This gene has 3 transcripts (splice variants) and 186 orthologues. Ubiquitous expression in bone marrow (RPKM 22.5), lymph node (RPKM 18.2) and 25 other tissues.

Summary

MED10 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

MED10 Products(1)

mRNA Protein Name
NM_032286.3 NP_115662.2 mediator of RNA polymerase II transcription subunit 10

MED10 Protein Structure

Med10

Med10: Transcription factor subunit Med10 of Mediator complex (9 - 127)

  • 0
  • 100
  • 135 a.a.
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 10

TRG-17

Related Diseases

Diseases Alias
Cri-Du-Chat Syndrome

5p Deletion Syndrome

5p Partial Monosomy Syndrome

Monosomy 5p

Cat Cry Syndrome

Chromosome 5p Deletion Syndrome

Cri Du Chat Syndrome

5p- Syndrome

5p Minus Syndrome

Chromosome 5p- Syndrome

Chromosome 5 Short Arm Deletion Syndrome

Chromosome 5p Deletion

Deletion 5p

Cri Du Chat

5p Partial Deletion Syndrome

Partial Deletion Of Short Arm Of Chromosome 5 Syndrome

Intellectual Developmental Disorder, Autosomal Dominant 48

Mental Retardation, Autosomal Dominant 48

MRD48

Autosomal Dominant Mental Retardation 48

Autosomal Dominant Intellectual Developmental Disorder 48

Junctional Epidermolysis Bullosa

Epidermolysis Bullosa, Junctional

Jeb

Epidermolysis Bullosa Atrophicans

Congenital Junctional Epidermolysis Bullosa

Epidermolysis Bullosa Junctional

Junctional Eb - [Epidermolysis Bullosa]

Jeb - [Junctional Epidermolysis Bullosa]

Lucidolytic Epidermolysis Bullosa

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MED10 RGD RGD:1310128
Mus musculus MED10 MGD MGI:106331
Macaca mulatta MED10 VGNC VGNC:110451
Bos taurus MED10 VGNC VGNC:31347
Canis familiaris MED10 VGNC VGNC:43118
Others MED10 NCBI