MAK16 - MAK16 homolog Gene

Homo sapiens

Also known as RBM13; MAK16L

Gene ID: 84549 | Gene type: protein coding

About MAK16

This gene has 5 transcripts (splice variants) and 203 orthologues. Ubiquitous expression in lymph node (RPKM 5.6), appendix (RPKM 5.5) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

MAK16 Products(1)

mRNA	Protein	Name
NM_032509.4	NP_115898.2	protein MAK16 homolog

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAK16 Protein Structure

Ribosomal_L28e

Mak16

0
100
200
300 a.a.

Protein Preferred Names

Protein Names

protein MAK16 homolog

NNP78

MAK16 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	MAK16	Q9BXY0	FRMD6	Homo sapiens	Q96NE9-2	Anti Tag CoIP	28514442
Intra	MAK16	Q9BXY0	FRMD6	Homo sapiens	Q96NE9-2	Y2H Prey Pooling	32296183
Intra	MAK16	Q9BXY0	FRMD6	Homo sapiens	Q96NE9-2	Y2H Array	32296183
Intra	MAK16	Q9BXY0	LIN7B	Homo sapiens	Q9HAP6	Validated Y2H	32296183
Intra	MAK16	Q9BXY0	LIN7B	Homo sapiens	Q9HAP6	Y2H Array	32296183
Intra	MAK16	Q9BXY0	LIN7B	Homo sapiens	Q9HAP6	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Intellectual Developmental Disorder, Autosomal Recessive 39

Severe Intellectual Disability-Short Stature-Behavioral Abnormalities-Facial Dysmorphism Syndrome	MRT39
Mental Retardation, Autosomal Recessive 39	Autosomal Recessive Intellectual Developmental Disorder 39
Mental Retardation, Autosomal Recessive, Type 39

Non-Syndromic X-Linked Intellectual Disability 14

Mrx14

Hypoglycemia, Leucine-Induced

Leucine-Sensitive Hypoglycemia Of Infancy	Leucine-Induced Hypoglycemia
LIH	Hypoglycemia Of Infancy, Leucine-Sensitive
Familial Infantile Hypoglycemia Precipitated By Leucine	Hypoglycemia Leucine Induced
Hypoglycemia Leucine-Induced

Autosomal Dominant Nocturnal Frontal Lobe Epilepsy

Adnfle	Autosomal Dominant Sleep-Related Hypermotor Epilepsy
Enfl	Benign Familial Infantile Seizures 6
Benign Familial Infantile Seizures, 6	Nocturnal Frontal Lobe Epilepsy-4
Enfl1	Epilepsy, Nocturnal Frontal Lobe, 1
Epilepsy, Nocturnal Frontal Lobe, Type 1

Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability	Non-Specific X-Linked Mental Retardation
X-Linked Non-Specific Intellectual Disability

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07990	MAK16 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MAK16	VGNC	VGNC:74281
Canis familiaris	MAK16	VGNC	VGNC:42932
Felis catus	MAK16	VGNC	VGNC:78524
Mus musculus	MAK16	MGD	MGI:1915170
Bos taurus	MAK16	VGNC	VGNC:31153
Rattus norvegicus	MAK16	RGD	RGD:1311297

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