2. Gene
  3. TXNDC17 - thioredoxin domain containing 17 Gene

TXNDC17 - thioredoxin domain containing 17 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TRP14; TXNL5

Gene ID: 84817 | Gene type: protein coding

About TXNDC17

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:6,641,060-6,644,541 (from NCBI)

This gene has 10 transcripts (splice variants) and 215 orthologues. Ubiquitous expression in colon (RPKM 14.3), esophagus (RPKM 13.2) and 25 other tissues.

Summary

Enables peroxidase activity and protein-disulfide reductase (NAD(P)) activity. Involved in tumor necrosis factor-mediated signaling pathway. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

TXNDC17 Products(1)

mRNA Protein Name
NM_032731.4 NP_116120.1 thioredoxin domain-containing protein 17
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables peroxidase activity IDA
IDA: Inferred from direct assay
14607844 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
14607844 GOA
enables protein-disulfide reductase (NAD(P)H) activity IDA
IDA: Inferred from direct assay
14607844 GOA
Biological Process GO Annotation Evidence Reference Source
involved in tumor necrosis factor-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
14607844 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
14607844 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thioredoxin domain-containing protein 17

14 kDa thioredoxin-related protein

Recombinant TXNDC17 Proteins

Cat. No. Product Name Accession Purity
HY-P77268 TXNDC17 Protein, Human A0A140VJY7 (M1-D123) ≥95%

Related Diseases

Diseases Alias
Parametritis

Pelvic Cellulitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15293 TXNDC17 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TXNDC17 VGNC VGNC:36538
Mus musculus TXNDC17 MGD MGI:1289248
Felis catus TXNDC17 VGNC VGNC:66728
Macaca mulatta TXNDC17 VGNC VGNC:104669
Rattus norvegicus TXNDC17 RGD RGD:1308868
Others TXNDC17 NCBI