EMILIN3 - elastin microfibril interfacer 3 Gene

Homo sapiens

Also known as EMILIN5; C20orf130; dJ620E11.4

Gene ID: 90187 | Gene type: protein coding

About EMILIN3

Cytogenetic location: 20q12 Genomic coordinates (GRCh38): 20:41,359,962-41,366,818 (from NCBI)

This gene has 1 transcript (splice variant), 260 orthologues and 4 paralogues. Ubiquitous expression in ovary (RPKM 6.7), duodenum (RPKM 6.1) and 24 other tissues.

Summary

Enables identical protein binding activity. Part of collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

EMILIN3 Products(1)

mRNA	Protein	Name
NM_052846.2	NP_443078.1	EMILIN-3 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EMILIN3 Protein Structure

EMI

0
200
400
600
766 a.a.

Protein Preferred Names

Protein Names

EMILIN-3

EMILIN-5

EMILIN3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	EMILIN3	Q9NT22	MEMO1	Homo sapiens	Q9Y316	Validated Y2H	32296183
Intra	EMILIN3	Q9NT22	EMILIN3	Homo sapiens	Q9NT22	Validated Y2H	32296183
Intra	EMILIN3	Q9NT22	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	32296183
Intra	EMILIN3	Q9NT22	EMILIN3	Homo sapiens	Q9NT22	Y2H Array	32296183
Intra	EMILIN3	Q9NT22	EMILIN3	Homo sapiens	Q9NT22	Y2H Prey Pooling	32296183
Intra	EMILIN3	Q9NT22	FBXO28	Homo sapiens	Q9NVF7	Y2H Prey Pooling	32296183
Intra	EMILIN3	Q9NT22	FBXO28	Homo sapiens	Q9NVF7	Validated Y2H	32296183
Intra	EMILIN3	Q9NT22	GORASP2	Homo sapiens	Q9H8Y8	Y2H Prey Pooling	32296183
Intra	EMILIN3	Q9NT22	FBXO28	Homo sapiens	Q9NVF7	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04352	EMILIN3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	EMILIN3	MGD	MGI:2389142
Canis familiaris	EMILIN3	VGNC	VGNC:40345
Felis catus	EMILIN3	VGNC	VGNC:61847
Rattus norvegicus	EMILIN3	RGD	RGD:1309607
Macaca mulatta	EMILIN3	VGNC	VGNC:107788
Bos taurus	EMILIN3	VGNC	VGNC:28475

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