2. Gene
  3. FBXO28 - F-box protein 28 Gene

FBXO28 - F-box protein 28 Gene

  • Gene
  • Protein
Homo sapiens (human)

Also known as Fbx28; DEE100; CENP-30

Gene ID: 23219 | Gene type: protein coding

About FBXO28

Summary

Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

FBXO28 Products(1)

mRNA Protein Name
NR_049764.2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Cellular Component GO Annotation Evidence Reference Source
located in kinetochore IDA
IDA: Inferred from direct assay
20813266 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box only protein 28

centromere protein 30

FBXO28 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra FBXO28 Q9NVF7 EMILIN1 Homo sapiens Q9Y6C2-2
Validated Y2H
32296183
Intra FBXO28 Q9NVF7 CTNNA3 Homo sapiens Q9UI47-2
Validated Y2H
32296183
Intra FBXO28 Q9NVF7 CAVIN1 Homo sapiens Q6NZI2
Y2H Array
32296183
Intra FBXO28 Q9NVF7 CAVIN1 Homo sapiens Q6NZI2
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 SKP1 Homo sapiens P63208
Validated Y2H
25416956
Intra FBXO28 Q9NVF7 SKP1 Homo sapiens P63208
Y2H Array
25416956
Intra FBXO28 Q9NVF7 SKP1 Homo sapiens P63208
Anti Tag CoIP
22632967
Intra FBXO28 Q9NVF7 EMILIN3 Homo sapiens Q9NT22
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 EMILIN3 Homo sapiens Q9NT22
Y2H Array
32296183
Intra FBXO28 Q9NVF7 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra FBXO28 Q9NVF7 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 SPAG5 Homo sapiens Q96R06
Validated Y2H
25416956
Intra FBXO28 Q9NVF7 SPAG5 Homo sapiens Q96R06
Y2H Array
25416956
Intra FBXO28 Q9NVF7 SPAG5 Homo sapiens Q96R06
Y2H Prey Pooling
25416956
Intra FBXO28 Q9NVF7 TRAF5 Homo sapiens O00463
Anti Tag CoIP
28514442
Intra FBXO28 Q9NVF7 TRAF5 Homo sapiens O00463
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 TRAF5 Homo sapiens O00463
Y2H Array
32296183
Intra FBXO28 Q9NVF7 TRAF5 Homo sapiens O00463
Anti Tag CoIP
33961781
Intra FBXO28 Q9NVF7 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra FBXO28 Q9NVF7 GOLGA2 Homo sapiens Q08379
Y2H
21516116
Intra FBXO28 Q9NVF7 GOLGA2 Homo sapiens Q08379
Validated Y2H
25416956
Intra FBXO28 Q9NVF7 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra FBXO28 Q9NVF7 EXOC7 Homo sapiens Q9UPT5-1
Validated Y2H
32296183
Intra FBXO28 Q9NVF7 PLEKHF2 Homo sapiens Q9H8W4
Y2H Prey Pooling
25416956
Intra FBXO28 Q9NVF7 PLEKHF2 Homo sapiens Q9H8W4
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
32296183
Intra FBXO28 Q9NVF7 SDCBP2 Homo sapiens Q9H190
Y2H Array
32296183
Intra FBXO28 Q9NVF7 SDCBP2 Homo sapiens Q9H190
Validated Y2H
25416956
Intra FBXO28 Q9NVF7 SDCBP2 Homo sapiens Q9H190
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 SDCBP2 Homo sapiens Q9H190
Y2H Prey Pooling
25416956
Intra FBXO28 Q9NVF7 GCC1 Homo sapiens Q96CN9
Y2H Array
32296183
Intra FBXO28 Q9NVF7 GCC1 Homo sapiens Q96CN9
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 AGGF1 Homo sapiens Q8N302
Y2H Array
32296183
Intra FBXO28 Q9NVF7 AGGF1 Homo sapiens Q8N302
Y2H Prey Pooling
32296183
Intra FBXO28 Q9NVF7 HOMER3 Homo sapiens Q9NSC5
Anti Tag CoIP
33961781
Intra FBXO28 Q9NVF7 STX1B Homo sapiens P61266
BRET
38225382
Cross: Cross-species interaction Intra: Intraspecies interaction