TMSB10 - thymosin beta 10 Gene

Homo sapiens

Also known as TB10; MIG12

Gene ID: 9168 | Gene type: protein coding

About TMSB10

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:84,905,656-84,906,671 (from NCBI)

This gene has 1 transcript (splice variant) and 67 orthologues. Ubiquitous expression in appendix (RPKM 826.8), colon (RPKM 808.9) and 25 other tissues.

Summary

Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration and sequestering of actin monomers. Predicted to be located in Cytoskeleton. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TMSB10 Products(1)

mRNA	Protein	Name
NM_021103.4	NP_066926.1	thymosin beta-10

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21044950	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMSB10 Protein Structure

Thymosin

0
44 a.a.

Protein Preferred Names

Protein Names

thymosin beta-10

migration-inducing gene 12

TMSB10 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TMSB10	P63313	KRTAP9-2	Homo sapiens	Q9BYQ4	Validated Y2H	25416956
Intra	TMSB10	P63313	ALAS1	Homo sapiens	P13196	Y2H Prey Pooling	25416956
Intra	TMSB10	P63313	ALAS1	Homo sapiens	P13196	Y2H Prey Pooling	32296183
Intra	TMSB10	P63313	ALAS1	Homo sapiens	P13196	Y2H Array	25416956
Intra	TMSB10	P63313	ALAS1	Homo sapiens	P13196	Y2H Array	32296183
Intra	TMSB10	P63313	POT1	Homo sapiens	Q9NUX5	Pull Down	21044950
Intra	TMSB10	P63313	POT1	Homo sapiens	Q9NUX5	BiFC	21044950

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Diamond-Blackfan Anemia 5

DBA5	Rpl35a-Related Diamond-Blackfan Anemia
Anemia, Diamond-Blackfan, Type 5

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14774	TMSB10 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TMSB10	VGNC	VGNC:106240
Mus musculus	TMSB10	MGD	MGI:109146
Rattus norvegicus	TMSB10	RGD	RGD:62022

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