CD302 - CD302 molecule Gene

Homo sapiens

Also known as DCL1; DCL-1; BIMLEC; CLEC13A

Gene ID: 9936 | Gene type: protein coding

About CD302

Cytogenetic location: 2q24.2 Genomic coordinates (GRCh38): 2:159,768,628-159,798,208 (from NCBI)

This gene has 4 transcripts (splice variants), 189 orthologues and 4 paralogues. Ubiquitous expression in liver (RPKM 51.3), lung (RPKM 34.3) and 25 other tissues.

Summary

CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis (Kato et al., 2007 [PubMed 17947679]).[supplied by OMIM, Aug 2008]

CD302 Products(3)

mRNA	Protein	Name
NM_001198763.2	NP_001185692.1	CD302 antigen isoform 2 precursor
NM_001198764.2	NP_001185693.1	CD302 antigen isoform 3 precursor
NM_014880.5	NP_055695.2	CD302 antigen isoform 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within phagocytosis	IDA IDA: Inferred from direct assay	17947679	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell cortex	IDA IDA: Inferred from direct assay	17947679	GOA
located in filopodium	IDA IDA: Inferred from direct assay	17947679	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CD302 Protein Structure

Lectin_C

0
100
200
232 a.a.

Protein Preferred Names

Protein Names

CD302 antigen

C-type lectin domain family 13, member A

CD302 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CD302	Q8IX05	IL10RA	Homo sapiens	Q13651	Y2H Prey Pooling	32296183
Intra	CD302	Q8IX05	IL10RA	Homo sapiens	Q13651	Y2H Array	32296183
Intra	CD302	Q8IX05	ARL13B	Homo sapiens	Q3SXY8	Y2H Prey Pooling	32296183
Intra	CD302	Q8IX05	ARL13B	Homo sapiens	Q3SXY8	Y2H Array	32296183
Intra	CD302	Q8IX05	GPX8	Homo sapiens	Q8TED1	Y2H Prey Pooling	32296183
Intra	CD302	Q8IX05	GPX8	Homo sapiens	Q8TED1	Validated Y2H	32296183
Intra	CD302	Q8IX05	GPX8	Homo sapiens	Q8TED1	Y2H Array	32296183
Intra	CD302	Q8IX05	FNDC9	Homo sapiens	Q8TBE3	Y2H Prey Pooling	32296183
Intra	CD302	Q8IX05	FNDC9	Homo sapiens	Q8TBE3	Y2H Array	32296183
Intra	CD302	Q8IX05	FNDC9	Homo sapiens	Q8TBE3	Validated Y2H	32296183
Intra	CD302	Q8IX05	OPRM1	Homo sapiens	P35372-10	Y2H Array	32296183
Intra	CD302	Q8IX05	OPRM1	Homo sapiens	P35372-10	Y2H Prey Pooling	32296183
Intra	CD302	Q8IX05	GET1	Homo sapiens	O00258	Y2H Prey Pooling	32296183
Intra	CD302	Q8IX05	GET1	Homo sapiens	O00258	Y2H Array	32296183
Intra	CD302	Q8IX05	IFNGR2	Homo sapiens	P38484	Y2H Array	32296183
Intra	CD302	Q8IX05	IFNGR2	Homo sapiens	P38484	Y2H Prey Pooling	32296183
Intra	CD302	Q8IX05	CD53	Homo sapiens	P19397	Y2H Prey Pooling	32296183
Intra	CD302	Q8IX05	CD53	Homo sapiens	P19397	Y2H Array	32296183
Intra	CD302	Q8IX05	ERGIC3	Homo sapiens	Q9Y282	Y2H Prey Pooling	32296183
Intra	CD302	Q8IX05	ERGIC3	Homo sapiens	Q9Y282	Validated Y2H	32296183
Intra	CD302	Q8IX05	ERGIC3	Homo sapiens	Q9Y282	Y2H Array	32296183
Intra	CD302	Q8IX05	IL7R	Homo sapiens	P16871	Y2H Array	32296183
Intra	CD302	Q8IX05	IL7R	Homo sapiens	P16871	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Hyperinsulinemic Hypoglycemia, Familial, 3

HHF3	Hyperinsulinism Due To Glucokinase Deficiency
Familial Hyperinsulinemic Hypoglycemia 3	Hyperinsulinemic Hypoglycemia Due To Glucokinase Deficiency
Hyperinsulinemic Hypoglycemia Familial 3	Congenital Hyperinsulinism
Persistent Hyperinsulinemic Hypoglycemia Of Infancy	Phhi
Hypoglycemia, Hyperinsulinemic, Familial, Type 3

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02233	CD302 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CD302	VGNC	VGNC:55333
Rattus norvegicus	CD302	RGD	RGD:1307606
Mus musculus	CD302	MGD	MGI:1913455

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