Glucocorticoid receptor agonist-5

Cat. No.: HY-164860 Purity: 98.36%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

Glucocorticoid receptor agonist-5 (compound 4), a glucocorticoid molecule, is a potent glucocorticoid receptor agonist. Glucocorticoid receptor agonist-5 shows anti-inflammatory and immunosuppressive activity. Glucocorticoid receptor agonist-5 is used as an ADC Cytotoxin for antibody-drug conjugate.

For research use only. We do not sell to patients.

Glucocorticoid receptor agonist-5 Chemical Structure

CAS No. : 2913231-72-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]

Traditional Cytotoxic Agents

Molecular Weight

584.70

Formula

C₃₆H₄₀O₇

CAS No.

2913231-72-6

Appearance

Solid

Color

White to off-white

SMILES

OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@@H](C6=CC=C(C=C6)CC7=CC=C(C=C7)CO)O2)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL (85.51 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7103 mL	8.5514 mL	17.1028 mL
5 mM	0.3421 mL	1.7103 mL	3.4206 mL
10 mM	0.1710 mL	0.8551 mL	1.7103 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.95%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (252 KB) HNMR (441 KB) RP-HPLC (249 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Xi Li, et al. Anti-bdca2 antibody-drug conjugate and use thereof. WO2024140838A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.7103 mL	8.5514 mL	17.1028 mL	42.7570 mL
	5 mM	0.3421 mL	1.7103 mL	3.4206 mL	8.5514 mL
	10 mM	0.1710 mL	0.8551 mL	1.7103 mL	4.2757 mL
	15 mM	0.1140 mL	0.5701 mL	1.1402 mL	2.8505 mL
	20 mM	0.0855 mL	0.4276 mL	0.8551 mL	2.1378 mL
	25 mM	0.0684 mL	0.3421 mL	0.6841 mL	1.7103 mL
	30 mM	0.0570 mL	0.2850 mL	0.5701 mL	1.4252 mL
	40 mM	0.0428 mL	0.2138 mL	0.4276 mL	1.0689 mL
	50 mM	0.0342 mL	0.1710 mL	0.3421 mL	0.8551 mL
	60 mM	0.0285 mL	0.1425 mL	0.2850 mL	0.7126 mL
	80 mM	0.0214 mL	0.1069 mL	0.2138 mL	0.5345 mL