2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. GluR6 antagonist-1

GluR6 antagonist-1 is a benzothiophene derivative, acting as a GluR6 antagonist. GluR6 antagonist-1 can be used for researching acute and chronic neurological disorders.

For research use only. We do not sell to patients.

GluR6 antagonist-1 Chemical Structure

GluR6 antagonist-1 Chemical Structure

CAS No. : 323176-64-3

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5 mg USD 110 In-stock
10 mg USD 170 In-stock
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Based on 1 publication(s) in Google Scholar

GluR6 antagonist-1 Related Antibodies

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Description

GluR6 antagonist-1 is a benzothiophene derivative, acting as a GluR6 antagonist. GluR6 antagonist-1 can be used for researching acute and chronic neurological disorders[1].

IC50 & Target

GluR6[1]
Molecular Weight

302.78

Formula

C15H11ClN2OS
CAS No.
Appearance

Solid

Color

Yellow to brown

SMILES

O=C(C1=C(Cl)C2=C(C=CC=C2)S1)NCC3=CC=CN=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 61 mg/mL (201.47 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3027 mL 16.5136 mL 33.0273 mL
5 mM 0.6605 mL 3.3027 mL 6.6055 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3027 mL 16.5136 mL 33.0273 mL 82.5682 mL
5 mM 0.6605 mL 3.3027 mL 6.6055 mL 16.5136 mL
10 mM 0.3303 mL 1.6514 mL 3.3027 mL 8.2568 mL
15 mM 0.2202 mL 1.1009 mL 2.2018 mL 5.5045 mL
20 mM 0.1651 mL 0.8257 mL 1.6514 mL 4.1284 mL
25 mM 0.1321 mL 0.6605 mL 1.3211 mL 3.3027 mL
30 mM 0.1101 mL 0.5505 mL 1.1009 mL 2.7523 mL
40 mM 0.0826 mL 0.4128 mL 0.8257 mL 2.0642 mL
50 mM 0.0661 mL 0.3303 mL 0.6605 mL 1.6514 mL
60 mM 0.0550 mL 0.2752 mL 0.5505 mL 1.3761 mL
80 mM 0.0413 mL 0.2064 mL 0.4128 mL 1.0321 mL
100 mM 0.0330 mL 0.1651 mL 0.3303 mL 0.8257 mL
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GluR6 antagonist-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GluR6 antagonist-1323176-64-3iGluRIonotropic glutamate receptorsbenzothiophene derivativeacute neurological disorderschronic neurological disordersInhibitorinhibitorinhibit

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