2. Vitamin D Related/Nuclear Receptor
  3. Androgen Receptor
  4. Gumelutamide

Gumelutamide is a tetrahydropyridopyrimidine compound, acting as an antiandrogen, antineoplastic agent. Gumelutamide is an androgen antagonist.

For research use only. We do not sell to patients.

Gumelutamide Chemical Structure

Gumelutamide Chemical Structure

CAS No. : 1831085-48-3

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10 mg USD 450 In-stock
25 mg USD 950 In-stock
50 mg USD 1500 In-stock
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Based on 1 publication(s) in Google Scholar

Gumelutamide Related Antibodies

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Description

Gumelutamide is a tetrahydropyridopyrimidine compound, acting as an antiandrogen, antineoplastic agent. Gumelutamide is an androgen antagonist[1][2].

Molecular Weight

420.89

Formula

C22H21ClN6O
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

N#CC1=CC=C(N2CC3=C(CC2)C(NC4=NC=C(C(C)(C)O)C=C4)=NC=N3)C=C1Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (118.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3759 mL 11.8796 mL 23.7592 mL
5 mM 0.4752 mL 2.3759 mL 4.7518 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3759 mL 11.8796 mL 23.7592 mL 59.3979 mL
5 mM 0.4752 mL 2.3759 mL 4.7518 mL 11.8796 mL
10 mM 0.2376 mL 1.1880 mL 2.3759 mL 5.9398 mL
15 mM 0.1584 mL 0.7920 mL 1.5839 mL 3.9599 mL
20 mM 0.1188 mL 0.5940 mL 1.1880 mL 2.9699 mL
25 mM 0.0950 mL 0.4752 mL 0.9504 mL 2.3759 mL
30 mM 0.0792 mL 0.3960 mL 0.7920 mL 1.9799 mL
40 mM 0.0594 mL 0.2970 mL 0.5940 mL 1.4849 mL
50 mM 0.0475 mL 0.2376 mL 0.4752 mL 1.1880 mL
60 mM 0.0396 mL 0.1980 mL 0.3960 mL 0.9900 mL
80 mM 0.0297 mL 0.1485 mL 0.2970 mL 0.7425 mL
100 mM 0.0238 mL 0.1188 mL 0.2376 mL 0.5940 mL
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Gumelutamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gumelutamide1831085-48-3Androgen ReceptorInhibitorinhibitorinhibit

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