2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. HDAC-IN-72

HDAC-IN-72 (compound 7j) is the most potent HDAC1 (IC50=0.65 μM), HDAC2 (IC50=0.78 μM), HDAC3 (IC50=1.70 μM) inhibitor and antiproliferative compound. HDAC-IN-72 can be used for breast cancer research.

For research use only. We do not sell to patients.

HDAC-IN-72 Chemical Structure

HDAC-IN-72 Chemical Structure

CAS No. : 763066-77-9

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HDAC-IN-72 Related Antibodies

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

HDAC-IN-72 (compound 7j) is the most potent HDAC1 (IC50=0.65 μM), HDAC2 (IC50=0.78 μM), HDAC3 (IC50=1.70 μM) inhibitor and antiproliferative compound. HDAC-IN-72 can be used for breast cancer research[1].

IC50 & Target

HDAC1

0.65 μM (IC50)

HDAC2

0.78 μM (IC50)

HDAC3

1.70 μM (IC50)

In Vitro

HDAC-IN-72 (0.1-50 μM, 48 h) shows good anti-proliferative activity against MCF-7 (IC50=0.83±1.41 μM) and T47D (IC50=1.4±1.85 μM) cell lines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HDAC-IN-72 Related Antibodies
Molecular Weight

359.42

Formula

C22H21N3O2
CAS No.
SMILES

O=C(NCC1=CC=C(C(NC2=CC=CC=C2N)=O)C=C1)C3=CC=C(C)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HDAC-IN-72 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC-IN-72763066-77-9HDACHistone deacetylasesHistone deacetylase inhibitorsbenzamide-based derivativesHDAC inhibitorInhibitorinhibitorinhibit

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