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HSL-IN-5 (Example 21) is a hormone sensitive lipase (HSL) inhibitor (IC50: 0.25 μM). HSL-IN-5 can be used for diabetes research.

For research use only. We do not sell to patients.

HSL-IN-5 Chemical Structure

HSL-IN-5 Chemical Structure

CAS No. : 308830-70-8

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10 mg USD 75 In-stock
25 mg USD 150 In-stock
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Description

HSL-IN-5 (Example 21) is a hormone sensitive lipase (HSL) inhibitor (IC50: 0.25 μM). HSL-IN-5 can be used for diabetes research[1].

Molecular Weight

388.38

Formula

C18H23F3N2O4

CAS No.
SMILES

O=C(N1CCC(CC1)C(NC2=CC=C(C=C2)OC(F)(F)F)=O)OC(C)(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (257.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5748 mL 12.8740 mL 25.7480 mL
5 mM 0.5150 mL 2.5748 mL 5.1496 mL
View the Complete Stock Solution Preparation Table
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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5748 mL 12.8740 mL 25.7480 mL 64.3699 mL
5 mM 0.5150 mL 2.5748 mL 5.1496 mL 12.8740 mL
10 mM 0.2575 mL 1.2874 mL 2.5748 mL 6.4370 mL
15 mM 0.1717 mL 0.8583 mL 1.7165 mL 4.2913 mL
20 mM 0.1287 mL 0.6437 mL 1.2874 mL 3.2185 mL
25 mM 0.1030 mL 0.5150 mL 1.0299 mL 2.5748 mL
30 mM 0.0858 mL 0.4291 mL 0.8583 mL 2.1457 mL
40 mM 0.0644 mL 0.3218 mL 0.6437 mL 1.6092 mL
50 mM 0.0515 mL 0.2575 mL 0.5150 mL 1.2874 mL
60 mM 0.0429 mL 0.2146 mL 0.4291 mL 1.0728 mL
80 mM 0.0322 mL 0.1609 mL 0.3218 mL 0.8046 mL
100 mM 0.0257 mL 0.1287 mL 0.2575 mL 0.6437 mL
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HSL-IN-5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HSL-IN-5
Cat. No.:
HY-164714
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