2. Immunology/Inflammation
  3. PSMA
  4. HYNIC-iPSMA TFA

HYNIC-iPSMA TFA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA TFA has excellent specificity and sensitivity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

HYNIC-iPSMA TFA Chemical Structure

HYNIC-iPSMA TFA Chemical Structure

CAS No. : 2375849-11-7

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1 mg USD 130 In-stock
5 mg USD 310 In-stock
10 mg USD 500 In-stock
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Based on 1 publication(s) in Google Scholar

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HYNIC-iPSMA TFA Related Antibodies

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Description

HYNIC-iPSMA TFA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA TFA has excellent specificity and sensitivity[1].

Molecular Weight

765.69

Formula

C33H38F3N7O11
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Hydrazinonicotinyl-Lys(Nal)-Urea-Glu
Sequence Shortening

Hydrazinonicotinyl-Lys(Nal)-Urea-Glu
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (130.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3060 mL 6.5301 mL 13.0601 mL
5 mM 0.2612 mL 1.3060 mL 2.6120 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3060 mL 6.5301 mL 13.0601 mL 32.6503 mL
5 mM 0.2612 mL 1.3060 mL 2.6120 mL 6.5301 mL
10 mM 0.1306 mL 0.6530 mL 1.3060 mL 3.2650 mL
15 mM 0.0871 mL 0.4353 mL 0.8707 mL 2.1767 mL
20 mM 0.0653 mL 0.3265 mL 0.6530 mL 1.6325 mL
25 mM 0.0522 mL 0.2612 mL 0.5224 mL 1.3060 mL
30 mM 0.0435 mL 0.2177 mL 0.4353 mL 1.0883 mL
40 mM 0.0327 mL 0.1633 mL 0.3265 mL 0.8163 mL
50 mM 0.0261 mL 0.1306 mL 0.2612 mL 0.6530 mL
60 mM 0.0218 mL 0.1088 mL 0.2177 mL 0.5442 mL
80 mM 0.0163 mL 0.0816 mL 0.1633 mL 0.4081 mL
100 mM 0.0131 mL 0.0653 mL 0.1306 mL 0.3265 mL
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HYNIC-iPSMA TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HYNIC-iPSMA2375849-11-7PSMAProstate-specific membrane antigen(99m)Tc-PSMA inhibitorClinical translationHYNIC-PSMA inhibitorProstate cancer imagingSPECTInhibitorinhibitorinhibit

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