2. Protein Tyrosine Kinase/RTK
  3. IGF-1R Src
  4. IGF-1R/SRC-IN-1

IGF-1R/SRC-IN-1 (Compound 3b) is an inhibitor for IGF-1R (IC50 is 63 μM) and SRC.

For research use only. We do not sell to patients.

IGF-1R/SRC-IN-1 Chemical Structure

IGF-1R/SRC-IN-1 Chemical Structure

CAS No. : 852367-46-5

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1 mg USD 40 In-stock
5 mg USD 85 In-stock
10 mg USD 130 In-stock
25 mg USD 260 In-stock
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Based on 1 publication(s) in Google Scholar

IGF-1R/SRC-IN-1 Related Antibodies

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Description

IGF-1R/SRC-IN-1 (Compound 3b) is an inhibitor for IGF-1R (IC50 is 63 μM) and SRC[1].

IC50 & Target

IC50: 63 μM (IGF-1R)
Molecular Weight

292.33

Formula

C18H16N2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(C1=CNC2=C1C=CC=C2)=O)NCC3=CC=C(C)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (106.90 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4208 mL 17.1040 mL 34.2079 mL
5 mM 0.6842 mL 3.4208 mL 6.8416 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4208 mL 17.1040 mL 34.2079 mL 85.5198 mL
5 mM 0.6842 mL 3.4208 mL 6.8416 mL 17.1040 mL
10 mM 0.3421 mL 1.7104 mL 3.4208 mL 8.5520 mL
15 mM 0.2281 mL 1.1403 mL 2.2805 mL 5.7013 mL
20 mM 0.1710 mL 0.8552 mL 1.7104 mL 4.2760 mL
25 mM 0.1368 mL 0.6842 mL 1.3683 mL 3.4208 mL
30 mM 0.1140 mL 0.5701 mL 1.1403 mL 2.8507 mL
40 mM 0.0855 mL 0.4276 mL 0.8552 mL 2.1380 mL
50 mM 0.0684 mL 0.3421 mL 0.6842 mL 1.7104 mL
60 mM 0.0570 mL 0.2851 mL 0.5701 mL 1.4253 mL
80 mM 0.0428 mL 0.2138 mL 0.4276 mL 1.0690 mL
100 mM 0.0342 mL 0.1710 mL 0.3421 mL 0.8552 mL
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IGF-1R/SRC-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IGF-1R/SRC-IN-1852367-46-5IGF-1RSrcInsulin-like growth factor-1 receptorA549NCI-H522OVCAR-8Inhibitorinhibitorinhibit

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