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  4. IMP2-IN-2

IMP2-IN-2 (compound 6) is a potent and selective IMP2 inhibitor, with IC50s of 120.9 μM and 236.7 μM for IMP2 interaction with RNA_A and RNA_B, respectively. IMP2-IN-2 can be used for the research of cancer.

For research use only. We do not sell to patients.

IMP2-IN-2 Chemical Structure

IMP2-IN-2 Chemical Structure

CAS No. : 1448353-39-6

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10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

IMP2-IN-2 Related Antibodies

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Description

IMP2-IN-2 (compound 6) is a potent and selective IMP2 inhibitor, with IC50s of 120.9 μM and 236.7 μM for IMP2 interaction with RNA_A and RNA_B, respectively. IMP2-IN-2 can be used for the research of cancer[1].

Molecular Weight

448.46

Formula

C22H19F3N2O3S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C1=C(NC(N(CC)CC2=CC=CC=C2)=O)C=C(C3=CC=C(C(F)(F)F)C=C3)S1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (222.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2299 mL 11.1493 mL 22.2985 mL
5 mM 0.4460 mL 2.2299 mL 4.4597 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2299 mL 11.1493 mL 22.2985 mL 55.7463 mL
5 mM 0.4460 mL 2.2299 mL 4.4597 mL 11.1493 mL
10 mM 0.2230 mL 1.1149 mL 2.2299 mL 5.5746 mL
15 mM 0.1487 mL 0.7433 mL 1.4866 mL 3.7164 mL
20 mM 0.1115 mL 0.5575 mL 1.1149 mL 2.7873 mL
25 mM 0.0892 mL 0.4460 mL 0.8919 mL 2.2299 mL
30 mM 0.0743 mL 0.3716 mL 0.7433 mL 1.8582 mL
40 mM 0.0557 mL 0.2787 mL 0.5575 mL 1.3937 mL
50 mM 0.0446 mL 0.2230 mL 0.4460 mL 1.1149 mL
60 mM 0.0372 mL 0.1858 mL 0.3716 mL 0.9291 mL
80 mM 0.0279 mL 0.1394 mL 0.2787 mL 0.6968 mL
100 mM 0.0223 mL 0.1115 mL 0.2230 mL 0.5575 mL
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IMP2-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IMP2-IN-21448353-39-6OthersIMP2RNA_ARNA_BcancerInhibitorinhibitorinhibit

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