2. Anti-infection
  3. Bacterial Antibiotic
  4. Kasugamycin hydrochloride

Kasugamycin hydrochloride  (Synonyms: Ksg hydrochloride)

Cat. No.: HY-B1864A Purity: 99.44%
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Kasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.

For research use only. We do not sell to patients.

Kasugamycin hydrochloride Chemical Structure

Kasugamycin hydrochloride Chemical Structure

CAS No. : 19408-46-9

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50 mg USD 50 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Kasugamycin hydrochloride:

Kasugamycin hydrochloride Related Antibodies

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1 Publications Citing Use of MCE Kasugamycin hydrochloride

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Description

Kasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation[1][2].

Molecular Weight

415.82

Formula

C14H26ClN3O9
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O.[H]Cl
Structure Classification
Initial Source

Streptomyces kasugaensis
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 8.33 mg/mL (20.03 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4049 mL 12.0244 mL 24.0489 mL
5 mM 0.4810 mL 2.4049 mL 4.8098 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4049 mL 12.0244 mL 24.0489 mL 60.1222 mL
5 mM 0.4810 mL 2.4049 mL 4.8098 mL 12.0244 mL
10 mM 0.2405 mL 1.2024 mL 2.4049 mL 6.0122 mL
15 mM 0.1603 mL 0.8016 mL 1.6033 mL 4.0081 mL
20 mM 0.1202 mL 0.6012 mL 1.2024 mL 3.0061 mL
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Kasugamycin hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kasugamycin19408-46-9KsgBacterialAntibioticpulmonary fibrosisribosomeInhibitorinhibitorinhibit

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