2. Epigenetics
  3. Histone Demethylase
  4. KDM2B-IN-1

KDM2B-IN-1 is a histone demethylase (kdm2b) inhibitor and can be used for hyperproliferative diseases research.

For research use only. We do not sell to patients.

KDM2B-IN-1 Chemical Structure

KDM2B-IN-1 Chemical Structure

CAS No. : 1965248-33-2

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5 mg USD 306 In-stock
10 mg USD 460 In-stock
25 mg USD 920 In-stock
50 mg USD 1380 In-stock
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Based on 1 publication(s) in Google Scholar

KDM2B-IN-1 Related Antibodies

Top Publications Citing Use of Products

View All Histone Demethylase Isoform Specific Products:

View All Isoforms
KDM1/LSD1 KDM2 KDM3 KDM4 KDM5 KDM6 KDM7

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Description

KDM2B-IN-1 is a histone demethylase (kdm2b) inhibitor and can be used for hyperproliferative diseases research[1].

Molecular Weight

402.55

Formula

C21H30N4O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=C2C(CCCC2)=C1)(N3C(N4CCN(C5CCC5)CC4)=NCC3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (12.42 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4842 mL 12.4208 mL 24.8416 mL
5 mM 0.4968 mL 2.4842 mL 4.9683 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4842 mL 12.4208 mL 24.8416 mL 62.1041 mL
5 mM 0.4968 mL 2.4842 mL 4.9683 mL 12.4208 mL
10 mM 0.2484 mL 1.2421 mL 2.4842 mL 6.2104 mL
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KDM2B-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KDM2B-IN-11965248-33-2Histone DemethylaseKDM2Bhyperproliferative diseasecancerstrokediabeteshepatomegalycardiovascular diseaseInhibitorinhibitorinhibit

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