2. GPCR/G Protein Neuronal Signaling
  3. Somatostatin Receptor
  4. L-054522

L-054522 is an agonist for somatostatin receptor subtype 2 with Kd of 0.01 nM. L-054522 inhibits growth hormone release from rat primary pituitary cell (IC50=0.05 nM) and glucagon and insulin release from isolated mouse pancreatic islet cell (IC50=0.05 nM and 12 nM).

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L-054522 Chemical Structure

L-054522 Chemical Structure

CAS No. : 214348-67-1

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L-054522 Related Antibodies

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Description

L-054522 is an agonist for somatostatin receptor subtype 2 with Kd of 0.01 nM. L-054522 inhibits growth hormone release from rat primary pituitary cell (IC50=0.05 nM) and glucagon and insulin release from isolated mouse pancreatic islet cell (IC50=0.05 nM and 12 nM)[1].

IC50 & Target

Kd: 0.01 nM (somatostatin receptor subtype 2)
Molecular Weight

645.79

Formula

C35H47N7O5
CAS No.
SMILES

O=C([C@H](CCCCN)NC([C@@H]([C@@H](C)C1=CNC2=C1C=CC=C2)NC(N3CCC(CC3)N4C5=CC=CC=C5NC4=O)=O)=O)OC(C)(C)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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L-054522 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-054522214348-67-1L054522L 054522Somatostatin ReceptorSSTRsSSTRSprague-Dawley rat C57BL/6J mouseCHOInhibitorinhibitorinhibit

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