LDV-FITC

Cat. No.: HY-P1188 Purity: 98.89%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (K_d: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn²⁺ respectively). LDV-FITC can be used to detect α4β1 integrin affinity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

LDV-FITC Chemical Structure

CAS No. : 1207610-07-8

Size	Price	Stock	Quantity
1 mg	USD 768	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of LDV-FITC:

LDV-FITC TFA Get quote

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•Related Small Molecules:

•Related Proteins:

View All Integrin Isoform Specific Products:

View All Isoforms

αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

α4β1 integrin^[1]

Molecular Weight

1368.51

Formula

C₆₉H₈₁N₁₁O₁₇S

CAS No.

1207610-07-8

Appearance

Solid

Color

Light yellow to yellow

Sequence

{4-((N′-2-methylphenyl)ureido)-phenylacetyl}-Leu-Asp-Val-Pro-Ala-Ala-{Lys(FITC)}

Sequence Shortening

{4-((N′-2-methylphenyl)ureido)-phenylacetyl}-LDVPAA-{Lys(FITC)}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (73.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.7307 mL	3.6536 mL	7.3072 mL
5 mM	0.1461 mL	0.7307 mL	1.4614 mL
10 mM	0.0731 mL	0.3654 mL	0.7307 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.89%

Select Batch:

Data Sheet (279 KB) SDS (252 KB)

COA (260 KB) RP-HPLC (107 KB) MS (198 KB)

Handling Instructions (2659 KB)

References

[1]. Hyduk SJ, et al. Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood. 2007 Jan 1;109(1):176-84. [Content Brief]

[2]. Chigaev A, et al. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. J Biol Chem. 2001 Dec 28;276(52):48670-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.7307 mL	3.6536 mL	7.3072 mL	18.2680 mL
	5 mM	0.1461 mL	0.7307 mL	1.4614 mL	3.6536 mL
	10 mM	0.0731 mL	0.3654 mL	0.7307 mL	1.8268 mL
	15 mM	0.0487 mL	0.2436 mL	0.4871 mL	1.2179 mL
	20 mM	0.0365 mL	0.1827 mL	0.3654 mL	0.9134 mL
	25 mM	0.0292 mL	0.1461 mL	0.2923 mL	0.7307 mL
	30 mM	0.0244 mL	0.1218 mL	0.2436 mL	0.6089 mL
	40 mM	0.0183 mL	0.0913 mL	0.1827 mL	0.4567 mL
	50 mM	0.0146 mL	0.0731 mL	0.1461 mL	0.3654 mL
	60 mM	0.0122 mL	0.0609 mL	0.1218 mL	0.3045 mL

LDV-FITC Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LDV-FITC1207610-07-8Integrinα4β1fluorescent peptideInhibitorinhibitorinhibit

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