2. Others Metabolic Enzyme/Protease Neuronal Signaling Membrane Transporter/Ion Channel Apoptosis
  3. Isotope-Labeled Compounds Endogenous Metabolite iGluR Ferroptosis Apoptosis
  4. L-Glutamic acid-13C5,15N

L-Glutamic acid-13C5,15N is the 13C- and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

For research use only. We do not sell to patients.

L-Glutamic acid-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N Chemical Structure

L-Glutamic acid-13C5,15N Chemical Structure

CAS No. : 202468-31-3

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10 mg USD 220 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Glutamic acid-13C5,15N:

L-Glutamic acid-13C5,15N Related Antibodies

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AMPA Receptor NMDA Receptor Kainate Receptor

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Description

L-Glutamic acid-13C5,15N is the 13C- and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Glutamic acid-13C5,15N Related Antibodies
Molecular Weight

153.09

Formula

13C5H915NO4
CAS No.
Unlabeled CAS

56-86-0
Appearance

Solid

Color

White to off-white

SMILES

O[13C]([13CH2][13CH2][13C@H]([15NH2])[13C](O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 31.25 mg/mL (204.13 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.5321 mL 32.6605 mL 65.3211 mL
5 mM 1.3064 mL 6.5321 mL 13.0642 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.5321 mL 32.6605 mL 65.3211 mL 163.3026 mL
5 mM 1.3064 mL 6.5321 mL 13.0642 mL 32.6605 mL
10 mM 0.6532 mL 3.2661 mL 6.5321 mL 16.3303 mL
15 mM 0.4355 mL 2.1774 mL 4.3547 mL 10.8868 mL
20 mM 0.3266 mL 1.6330 mL 3.2661 mL 8.1651 mL
25 mM 0.2613 mL 1.3064 mL 2.6128 mL 6.5321 mL
30 mM 0.2177 mL 1.0887 mL 2.1774 mL 5.4434 mL
40 mM 0.1633 mL 0.8165 mL 1.6330 mL 4.0826 mL
50 mM 0.1306 mL 0.6532 mL 1.3064 mL 3.2661 mL
60 mM 0.1089 mL 0.5443 mL 1.0887 mL 2.7217 mL
80 mM 0.0817 mL 0.4083 mL 0.8165 mL 2.0413 mL
100 mM 0.0653 mL 0.3266 mL 0.6532 mL 1.6330 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Glutamic acid-13C5,15N Related Classifications

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Keywords:

L-Glutamic acid-13C5,15N202468-31-3Isotope-Labeled CompoundsEndogenous MetaboliteiGluRFerroptosisApoptosisIonotropic glutamate receptorsInhibitorinhibitorinhibit

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