Ligustrosidic acid

Name: Ligustrosidic acid
Brand: MedChemExpress
SKU: HY-N6874
Rating: 4.5 (1 reviews)

Cat. No.: HY-N6874 Purity: 94.80%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Ligustrosidic acid is a natural compound isolated from ligustrum japonicum and ligustrum lucidum.

For research use only. We do not sell to patients.

Ligustrosidic acid Chemical Structure

CAS No. : 96382-89-7

Size	Price	Stock	Quantity
5 mg	USD 269	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 457	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Ligustrosidic acid is a natural compound isolated from ligustrum japonicum and ligustrum lucidum^[1].

Molecular Weight

554.50

Formula

C₂₅H₃₀O₁₄

CAS No.

96382-89-7

Appearance

Solid

Color

Off-white to light yellow

SMILES

OC1=CC=C(CCOC(CC(C(C(OC)=O)=COC2O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)(/C2=C\C(O)=O)[H])=O)C=C1

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (180.34 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8034 mL	9.0171 mL	18.0343 mL
5 mM	0.3607 mL	1.8034 mL	3.6069 mL
10 mM	0.1803 mL	0.9017 mL	1.8034 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (4.51 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (4.51 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (4.51 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 94.80%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (248 KB) RP-HPLC (243 KB)

Handling Instructions (2659 KB)

References

[1]. Fukuyama Y1, et al. New Secoiridoid Glucosides from Ligustrum japonicum.Planta Med. 1987 Oct;53(5):427-31. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.8034 mL	9.0171 mL	18.0343 mL	45.0857 mL
	5 mM	0.3607 mL	1.8034 mL	3.6069 mL	9.0171 mL
	10 mM	0.1803 mL	0.9017 mL	1.8034 mL	4.5086 mL
	15 mM	0.1202 mL	0.6011 mL	1.2023 mL	3.0057 mL
	20 mM	0.0902 mL	0.4509 mL	0.9017 mL	2.2543 mL
	25 mM	0.0721 mL	0.3607 mL	0.7214 mL	1.8034 mL
	30 mM	0.0601 mL	0.3006 mL	0.6011 mL	1.5029 mL
	40 mM	0.0451 mL	0.2254 mL	0.4509 mL	1.1271 mL
	50 mM	0.0361 mL	0.1803 mL	0.3607 mL	0.9017 mL
	60 mM	0.0301 mL	0.1503 mL	0.3006 mL	0.7514 mL
	80 mM	0.0225 mL	0.1127 mL	0.2254 mL	0.5636 mL
	100 mM	0.0180 mL	0.0902 mL	0.1803 mL	0.4509 mL