2. Stem Cell/Wnt
  3. YAP
  4. LM-41

LM-41 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2. LM-41 inhibits migration of human MDA-MB-231 breast cancer cells.

For research use only. We do not sell to patients.

LM-41 Chemical Structure

LM-41 Chemical Structure

CAS No. : 2996821-30-6

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5 mg USD 222 In-stock
10 mg USD 333 In-stock
25 mg USD 666 In-stock
50 mg USD 1000 In-stock
100 mg USD 1300 In-stock
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LM-41 Related Antibodies

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Description

LM-41 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2. LM-41 inhibits migration of human MDA-MB-231 breast cancer cells[1].

Molecular Weight

307.32

Formula

C19H14FNO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C1=CC=C(F)C=C1NC2=CC(C3=CC=CC=C3)=CC=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 140 mg/mL (455.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2539 mL 16.2697 mL 32.5394 mL
5 mM 0.6508 mL 3.2539 mL 6.5079 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2539 mL 16.2697 mL 32.5394 mL 81.3484 mL
5 mM 0.6508 mL 3.2539 mL 6.5079 mL 16.2697 mL
10 mM 0.3254 mL 1.6270 mL 3.2539 mL 8.1348 mL
15 mM 0.2169 mL 1.0846 mL 2.1693 mL 5.4232 mL
20 mM 0.1627 mL 0.8135 mL 1.6270 mL 4.0674 mL
25 mM 0.1302 mL 0.6508 mL 1.3016 mL 3.2539 mL
30 mM 0.1085 mL 0.5423 mL 1.0846 mL 2.7116 mL
40 mM 0.0813 mL 0.4067 mL 0.8135 mL 2.0337 mL
50 mM 0.0651 mL 0.3254 mL 0.6508 mL 1.6270 mL
60 mM 0.0542 mL 0.2712 mL 0.5423 mL 1.3558 mL
80 mM 0.0407 mL 0.2034 mL 0.4067 mL 1.0169 mL
100 mM 0.0325 mL 0.1627 mL 0.3254 mL 0.8135 mL
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LM-41 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LM-412996821-30-6LM41LM 41YAPYes-associated proteinTEAD inhibitorCTGFCyr61AxlNF2migrationInhibitorinhibitorinhibit

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