LOXL2-IN-1 tosylate

Cat. No.: HY-170573A Purity: 99.90%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

LOX-IN-5 tosylate (compound 22) is a selective and orally active lysyl oxidase-like 2 (LOXL2) inhibitor with an IC₅₀ of <300 nM. LOX-IN-5 tosylate possess anti-fibrosis properties.

For research use only. We do not sell to patients.

LOXL2-IN-1 tosylate Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of LOXL2-IN-1 tosylate:

LOXL2-IN-1 Get quote

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Monoamine Oxidase Isoform Specific Products:

View All Isoforms

MAO-A MAO-B

Biological Activity
Purity & Documentation
References
Customer Review

Description

LOX-IN-5 tosylate (compound 22) is a selective and orally active lysyl oxidase-like 2 (LOXL2) inhibitor with an IC₅₀ of <300 nM. LOX-IN-5 tosylate possess anti-fibrosis properties^[1].

Molecular Weight

588.71

Formula

C₂₈H₃₃FN₄O₅S₂

Appearance

Solid

Color

White to off-white

SMILES

CC1=CC=C(S(=O)(O)=O)C=C1.NC/C=C(CN2C3=CC=CN=C3C(CC4=CN=C(C=C4)S(C)(=O)=O)=C2C(C)C)\F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL (84.93 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6986 mL	8.4931 mL	16.9863 mL
5 mM	0.3397 mL	1.6986 mL	3.3973 mL
10 mM	0.1699 mL	0.8493 mL	1.6986 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.90%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (257 KB) LCMS (118 KB)

Handling Instructions (2659 KB)

References

[1]. INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF. WO/2017/136871.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6986 mL	8.4931 mL	16.9863 mL	42.4657 mL
	5 mM	0.3397 mL	1.6986 mL	3.3973 mL	8.4931 mL
	10 mM	0.1699 mL	0.8493 mL	1.6986 mL	4.2466 mL
	15 mM	0.1132 mL	0.5662 mL	1.1324 mL	2.8310 mL
	20 mM	0.0849 mL	0.4247 mL	0.8493 mL	2.1233 mL
	25 mM	0.0679 mL	0.3397 mL	0.6795 mL	1.6986 mL
	30 mM	0.0566 mL	0.2831 mL	0.5662 mL	1.4155 mL
	40 mM	0.0425 mL	0.2123 mL	0.4247 mL	1.0616 mL
	50 mM	0.0340 mL	0.1699 mL	0.3397 mL	0.8493 mL
	60 mM	0.0283 mL	0.1416 mL	0.2831 mL	0.7078 mL
	80 mM	0.0212 mL	0.1062 mL	0.2123 mL	0.5308 mL