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  4. LRH-1 modulator-1

LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 shows anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces anti-inflammatory cytokine IL-10, and reduces inflammatory cytokine IL-1b and TNFa.

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LRH-1 modulator-1 Chemical Structure

LRH-1 modulator-1 Chemical Structure

CAS No. : 2244781-29-9

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Description

LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 shows anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces anti-inflammatory cytokine IL-10, and reduces inflammatory cytokine IL-1b and TNFa[1].

Molecular Weight

464.66

Formula

C28H36N2O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C=C(C1=CC=CC=C1)[C@]([C@](C2)([H])[C@H]3N[S](N)(=O)=O)(CC3)C(C4=CC=CC=C4)=C2CCCCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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LRH-1 modulator-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LRH-1 modulator-12244781-29-9Othersliver receptor homologinflammatory bowel diseasesIBDagonistnuclear receptorx-ray crystallographydrug discoveryInhibitorinhibitorinhibit

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