Mcl-1 inhibitor 17

Cat. No.: HY-155472 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Mcl-1 inhibitor 17 is a Mcl-1 protein inhibitor. Mcl-1 inhibitor 17 can be used for the research of cancer and other diseases.

For research use only. We do not sell to patients.

Mcl-1 inhibitor 17 Chemical Structure

CAS No. : 892250-00-9

Size	Price	Stock	Quantity
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Mcl-1 inhibitor 17 is a Mcl-1 protein inhibitor. Mcl-1 inhibitor 17 can be used for the research of cancer and other diseases^[1].

Molecular Weight

456.51

Formula

C₂₇H₂₅FN₄O₂

CAS No.

892250-00-9

Appearance

Solid

Color

White to light yellow

SMILES

O=C(N1CCN(CC1)C2=CC=C(C=C2)F)C3=CN=C(C4=C3C=CC=C4)NC5=CC=C(C=C5)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (219.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1905 mL	10.9527 mL	21.9053 mL
5 mM	0.4381 mL	2.1905 mL	4.3811 mL
10 mM	0.2191 mL	1.0953 mL	2.1905 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (253 KB) HNMR (206 KB)

Handling Instructions (2659 KB)

References

[1]. Zaneta Nikolovska-Coleska, et al. Small molecule inhibitors of mcl-1 and uses thereof. Patent. WO2015153959A2.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1905 mL	10.9527 mL	21.9053 mL	54.7633 mL
	5 mM	0.4381 mL	2.1905 mL	4.3811 mL	10.9527 mL
	10 mM	0.2191 mL	1.0953 mL	2.1905 mL	5.4763 mL
	15 mM	0.1460 mL	0.7302 mL	1.4604 mL	3.6509 mL
	20 mM	0.1095 mL	0.5476 mL	1.0953 mL	2.7382 mL
	25 mM	0.0876 mL	0.4381 mL	0.8762 mL	2.1905 mL
	30 mM	0.0730 mL	0.3651 mL	0.7302 mL	1.8254 mL
	40 mM	0.0548 mL	0.2738 mL	0.5476 mL	1.3691 mL
	50 mM	0.0438 mL	0.2191 mL	0.4381 mL	1.0953 mL
	60 mM	0.0365 mL	0.1825 mL	0.3651 mL	0.9127 mL
	80 mM	0.0274 mL	0.1369 mL	0.2738 mL	0.6845 mL
	100 mM	0.0219 mL	0.1095 mL	0.2191 mL	0.5476 mL