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Me-IQ (Methyl-IQ), an orally active heterocyclic amine, is carcinogenic and mutagenic. Me-IQ is several hundred-fold more mutagenic in liver than in lung microsomal preparations from uninduced mice and rabbits.

For research use only. We do not sell to patients.

Me-IQ Chemical Structure

Me-IQ Chemical Structure

CAS No. : 77094-11-2

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1 mg USD 170 In-stock
5 mg USD 425 In-stock
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Based on 1 publication(s) in Google Scholar

Me-IQ Related Antibodies

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  • Purity & Documentation

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Description

Me-IQ (Methyl-IQ), an orally active heterocyclic amine, is carcinogenic and mutagenic. Me-IQ is several hundred-fold more mutagenic in liver than in lung microsomal preparations from uninduced mice and rabbits[1][2].

In Vitro

Me-IQ (Methyl-IQ; diet containing 0.04% or 0.01%) causes squamous cell carcinomas and papillomas of the forestomach to develop at high incidences in mice. About 40% of the squamous cell carcinomas induced in the forestomach by 0.04% MeIQ metastasized to the liver[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Me-IQ Related Antibodies
Molecular Weight

212.25

Formula

C12H12N4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

NC(N1C)=NC2=C1C(C)=CC3=C2C=CC=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 6.37 mg/mL (30.01 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7114 mL 23.5571 mL 47.1143 mL
5 mM 0.9423 mL 4.7114 mL 9.4229 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.48%

COA (254 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7114 mL 23.5571 mL 47.1143 mL 117.7856 mL
5 mM 0.9423 mL 4.7114 mL 9.4229 mL 23.5571 mL
10 mM 0.4711 mL 2.3557 mL 4.7114 mL 11.7786 mL
15 mM 0.3141 mL 1.5705 mL 3.1410 mL 7.8524 mL
20 mM 0.2356 mL 1.1779 mL 2.3557 mL 5.8893 mL
25 mM 0.1885 mL 0.9423 mL 1.8846 mL 4.7114 mL
30 mM 0.1570 mL 0.7852 mL 1.5705 mL 3.9262 mL
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Me-IQ Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Me-IQ77094-11-2Methyl-IQOthersOrallyheterocyclic aminecarcinogenicmutageniclung microsomalInhibitorinhibitorinhibit

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