1. Metabolic Enzyme/Protease
  2. Elastase Cathepsin
  3. MeOSuc-AAPV-CMK

MeOSuc-AAPV-CMK  (Synonyms: Elastase Inhibitor III)

Cat. No.: HY-136888 Purity: 99.73%
Handling Instructions Technical Support

MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor. MeOSuc-AAPV-CMK also inhibits cathepsin G and proteinase 3.MeOSuc-AAPV-CMK blocks the cleavage of adiponectin by leukocyte elastase.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

MeOSuc-AAPV-CMK Chemical Structure

MeOSuc-AAPV-CMK Chemical Structure

CAS No. : 65144-34-5

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Based on 1 publication(s) in Google Scholar

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Description

MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor. MeOSuc-AAPV-CMK also inhibits cathepsin G and proteinase 3.MeOSuc-AAPV-CMK blocks the cleavage of adiponectin by leukocyte elastase[1].

Molecular Weight

502.99

Formula

C22H35ClN4O7

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{MeOSuc}-Ala-Ala-Pro-Val-{CMK}

Sequence Shortening

{MeOSuc}-AAPV-{CMK}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (248.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9881 mL 9.9406 mL 19.8811 mL
5 mM 0.3976 mL 1.9881 mL 3.9762 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9881 mL 9.9406 mL 19.8811 mL 49.7028 mL
5 mM 0.3976 mL 1.9881 mL 3.9762 mL 9.9406 mL
10 mM 0.1988 mL 0.9941 mL 1.9881 mL 4.9703 mL
15 mM 0.1325 mL 0.6627 mL 1.3254 mL 3.3135 mL
20 mM 0.0994 mL 0.4970 mL 0.9941 mL 2.4851 mL
25 mM 0.0795 mL 0.3976 mL 0.7952 mL 1.9881 mL
30 mM 0.0663 mL 0.3314 mL 0.6627 mL 1.6568 mL
40 mM 0.0497 mL 0.2485 mL 0.4970 mL 1.2426 mL
50 mM 0.0398 mL 0.1988 mL 0.3976 mL 0.9941 mL
60 mM 0.0331 mL 0.1657 mL 0.3314 mL 0.8284 mL
80 mM 0.0249 mL 0.1243 mL 0.2485 mL 0.6213 mL
100 mM 0.0199 mL 0.0994 mL 0.1988 mL 0.4970 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MeOSuc-AAPV-CMK
Cat. No.:
HY-136888
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