1. Natural Products
  2. Plants Alkaloids
  3. Rutaceae
  4. Clausena lansium (Lour.) Skeels
  5. Methyl carbazole-3-carboxylate

Methylcarbazole-3-carboxylate is a carbazole alkaloid can be isolated from the peel of Clausena lansium (Lour.) Skeels.

For research use only. We do not sell to patients.

Methyl carbazole-3-carboxylate Chemical Structure

Methyl carbazole-3-carboxylate Chemical Structure

CAS No. : 97931-41-4

Size Price Stock Quantity
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Methylcarbazole-3-carboxylate is a carbazole alkaloid can be isolated from the peel of Clausena lansium (Lour.) Skeels[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
36.9 μM
Compound: 5
Growth inhibition of human HepG2 cells after 48 hrs by WST-8 based CCK8 assay
Growth inhibition of human HepG2 cells after 48 hrs by WST-8 based CCK8 assay
[PMID: 22093759]
KB IC50
59.7 μM
Compound: 18
Cytotoxicity against human KB cells by resazurin reduction assay
Cytotoxicity against human KB cells by resazurin reduction assay
[PMID: 22482432]
MCF7 IC50
169.8 μM
Compound: 18
Cytotoxicity against human MCF7 cells by resazurin reduction assay
Cytotoxicity against human MCF7 cells by resazurin reduction assay
[PMID: 22482432]
NCI-H187 IC50
95.8 μM
Compound: 18
Cytotoxicity against human NCI-H187 cells by resazurin reduction assay
Cytotoxicity against human NCI-H187 cells by resazurin reduction assay
[PMID: 22482432]
Neutrophil IC50
> 10 μM
Compound: 20
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
[PMID: 24798144]
Neutrophil IC50
4.3 μM
Compound: 20
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
[PMID: 24798144]
Molecular Weight

225.24

Formula

C14H11NO2

CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

COC(C1=CC2=C(C=C1)NC3=CC=CC=C23)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (554.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4397 mL 22.1985 mL 44.3971 mL
5 mM 0.8879 mL 4.4397 mL 8.8794 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4397 mL 22.1985 mL 44.3971 mL 110.9927 mL
5 mM 0.8879 mL 4.4397 mL 8.8794 mL 22.1985 mL
10 mM 0.4440 mL 2.2199 mL 4.4397 mL 11.0993 mL
15 mM 0.2960 mL 1.4799 mL 2.9598 mL 7.3995 mL
20 mM 0.2220 mL 1.1099 mL 2.2199 mL 5.5496 mL
25 mM 0.1776 mL 0.8879 mL 1.7759 mL 4.4397 mL
30 mM 0.1480 mL 0.7400 mL 1.4799 mL 3.6998 mL
40 mM 0.1110 mL 0.5550 mL 1.1099 mL 2.7748 mL
50 mM 0.0888 mL 0.4440 mL 0.8879 mL 2.2199 mL
60 mM 0.0740 mL 0.3700 mL 0.7400 mL 1.8499 mL
80 mM 0.0555 mL 0.2775 mL 0.5550 mL 1.3874 mL
100 mM 0.0444 mL 0.2220 mL 0.4440 mL 1.1099 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Methyl carbazole-3-carboxylate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Methyl carbazole-3-carboxylate
Cat. No.:
HY-N3288
Quantity:
MCE Japan Authorized Agent: