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  5. Methyl yellow

Methyl yellow  (Synonyms: Solvent Yellow 2; Dimethyl yellow)

Cat. No.: HY-W025785
Handling Instructions

Molarity Calculator

Methyl yellow (Solvent Yellow 2) is a pH indicator. Methyl yellow appears red at low pH, and becomes yellow above pH 4.0.

For research use only. We do not sell to patients.

Methyl yellow Chemical Structure

Methyl yellow Chemical Structure

CAS No. : 60-11-7

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Other Forms of Methyl yellow:

Methyl yellow Related Antibodies

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Description

Methyl yellow (Solvent Yellow 2) is a pH indicator. Methyl yellow appears red at low pH, and becomes yellow above pH 4.0[1].

In Vivo

Methyl yellow can be used in animal modeling to create hepatic tumor models. After administration of Methyl yellow, the levels of dihydroxycholan acid (DHA) decrease in rats that secrete more than 10 mg/100 g body weight of trihydroxycholan acid (THA) daily. The bile volume also increases in the treated rats, and there is a strong correlation between DHA levels and bile volume[2].

Induction of liver tumor[2]
Background
Methyl yellow can degrade cholesterol into bile acids, and specific disorders in bile acid metabolism may lead to the generation of endogenous carcinogens, which can induce liver tumors.
Specific Mmodeling Methods
Rat: G.G. strain • male • 3-4 months old
Administration: 0.06 % of diet • feed • 2-5 months
Note
(1) Create a fistula in the rat's bile duct, and collect bile from days 2 to 4 after cannulation, discarding the bile from the day before death.
(2) The rats were either killed after a period of bile discharge or euthanized with ether. A histological examination was performed on the livers of the euthanized mice.
Modeling Indicators
Phenotypic observation: Increased bile production and bile drainage lead to bile duct hyperplasia and liver necrosis; the survival time of rats after bile duct cannulation is shortened, and they experience significant weight loss.
Correlated Product(s): /
Opposite Product(s): /

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

225.29

Formula

C14H15N3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CN(C)C1=CC=C(/N=N/C2=CC=CC=C2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Methyl yellow Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methyl yellow60-11-7Solvent Yellow 2 Dimethyl yellowSolvent Yellow2Solvent Yellow-2OthersInhibitorinhibitorinhibit

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