Metronidazole-¹³C₂,¹⁵N₂

Name: Metronidazole- 13 C 2 , 15 N 2
Brand: MedChemExpress
SKU: HY-B0318S
Rating: 4.5 (1 reviews)

Cat. No.: HY-B0318S Purity: 99.30%: FAQs
Data Sheet SDS COA Handling Instructions

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Metronidazole-¹³C₂,¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.

For research use only. We do not sell to patients.

Metronidazole-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N<sub>2</sub> Chemical Structure

Metronidazole-¹³C₂,¹⁵N₂ Chemical Structure

CAS No. : 1173020-03-5

Size	Price	Stock	Quantity
1 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Metronidazole-¹³C₂,¹⁵N₂:

Metronidazole In-stock
Metronidazole-d₃ Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Metronidazole-¹³C₂,¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

175.13

Formula

C₄¹³C₂H₉N¹⁵N₂O₃

CAS No.

1173020-03-5

Unlabeled CAS

443-48-1

Appearance

Solid

Color

Off-white to light yellow

SMILES

OCC[15N]1C([N+]([O-])=O)=C[15N]=[13C]1[13CH3]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 35 mg/mL (199.85 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.7100 mL	28.5502 mL	57.1004 mL
5 mM	1.1420 mL	5.7100 mL	11.4201 mL
10 mM	0.5710 mL	2.8550 mL	5.7100 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.30%

Select Batch:

Data Sheet (275 KB) SDS (419 KB)

COA (253 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. In Schaechter, M.; Engleberg, N. C.; DiRita, V. J. et al. Schaechter's Mechanisms of Microbial Disease. Hagerstown, MD: Lippincott Williams & Wilkins. p. 28.

[3]. http://www.drugs.com/monograph/metronidazole.html

[4]. Cohen, S.H., et al., Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol, [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.7100 mL	28.5502 mL	57.1004 mL	142.7511 mL
	5 mM	1.1420 mL	5.7100 mL	11.4201 mL	28.5502 mL
	10 mM	0.5710 mL	2.8550 mL	5.7100 mL	14.2751 mL
	15 mM	0.3807 mL	1.9033 mL	3.8067 mL	9.5167 mL
	20 mM	0.2855 mL	1.4275 mL	2.8550 mL	7.1376 mL
	25 mM	0.2284 mL	1.1420 mL	2.2840 mL	5.7100 mL
	30 mM	0.1903 mL	0.9517 mL	1.9033 mL	4.7584 mL
	40 mM	0.1428 mL	0.7138 mL	1.4275 mL	3.5688 mL
	50 mM	0.1142 mL	0.5710 mL	1.1420 mL	2.8550 mL
	60 mM	0.0952 mL	0.4758 mL	0.9517 mL	2.3792 mL
	80 mM	0.0714 mL	0.3569 mL	0.7138 mL	1.7844 mL
	100 mM	0.0571 mL	0.2855 mL	0.5710 mL	1.4275 mL