2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. (-)-GSK598809 hydrochloride

(-)-GSK598809 hydrochloride  (Synonyms: (1S,5R)-GSK598809 hydrochloride)

Cat. No.: HY-19654C Purity: 99.64%
COA Handling Instructions

Molarity Calculator

(-)-GSK598809 is an isomer of GSK598809. GSK598809 is a potent and selective dopamine D3 Receptor (DRD3) antagonist.

For research use only. We do not sell to patients.

(-)-GSK598809 hydrochloride Chemical Structure

(-)-GSK598809 hydrochloride Chemical Structure

CAS No. : 863766-31-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 217 In-stock
Solution
10 mM * 1 mL in DMSO USD 217 In-stock
Solid
5 mg USD 190 In-stock
10 mg USD 290 In-stock
25 mg USD 490 In-stock
50 mg USD 730 In-stock
100 mg USD 990 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (-)-GSK598809 hydrochloride:

(-)-GSK598809 hydrochloride Related Antibodies

Top Publications Citing Use of Products

View All Dopamine Receptor Isoform Specific Products:

View All Isoforms
Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

(-)-GSK598809 is an isomer of GSK598809. GSK598809 is a potent and selective dopamine D3 Receptor (DRD3) antagonist.

IC50 & Target[1]

D3 Receptor

 

Molecular Weight

517.97

Formula

C22H24ClF4N5OS
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=C(C2=NN=C(SCCCN3C[C@@]4(C5=CC=C(C(F)(F)F)C=C5F)C[C@@]4([H])C3)N2C)OC=N1.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (241.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9306 mL 9.6531 mL 19.3061 mL
5 mM 0.3861 mL 1.9306 mL 3.8612 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.64%

COA (251 KB) HNMR (276 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9306 mL 9.6531 mL 19.3061 mL 48.2653 mL
5 mM 0.3861 mL 1.9306 mL 3.8612 mL 9.6531 mL
10 mM 0.1931 mL 0.9653 mL 1.9306 mL 4.8265 mL
15 mM 0.1287 mL 0.6435 mL 1.2871 mL 3.2177 mL
20 mM 0.0965 mL 0.4827 mL 0.9653 mL 2.4133 mL
25 mM 0.0772 mL 0.3861 mL 0.7722 mL 1.9306 mL
30 mM 0.0644 mL 0.3218 mL 0.6435 mL 1.6088 mL
40 mM 0.0483 mL 0.2413 mL 0.4827 mL 1.2066 mL
50 mM 0.0386 mL 0.1931 mL 0.3861 mL 0.9653 mL
60 mM 0.0322 mL 0.1609 mL 0.3218 mL 0.8044 mL
80 mM 0.0241 mL 0.1207 mL 0.2413 mL 0.6033 mL
100 mM 0.0193 mL 0.0965 mL 0.1931 mL 0.4827 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

(-)-GSK598809 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-GSK598809863766-31-8(1S,5R)-GSK598809Dopamine ReceptorInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
(-)-GSK598809 hydrochloride
Cat. No.:
HY-19654C
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.