2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. (-)-Isoproterenol hydrochloride

(-)-Isoproterenol hydrochloride  (Synonyms: Levisoprenaline hydrochloride; Proternol L hydrochloride)

Cat. No.: HY-B1670A Purity: 99.97%
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(-)-Isoproterenol (Levisoprenaline; Proternol L) hydrochloride is a β-adrenoceptor agonist. (-)-Isoproterenol induces ventricular remodeling.

For research use only. We do not sell to patients.

(-)-Isoproterenol hydrochloride Chemical Structure

(-)-Isoproterenol hydrochloride Chemical Structure

CAS No. : 5984-95-2

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1 mg USD 141 In-stock
5 mg USD 285 In-stock
10 mg USD 456 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of (-)-Isoproterenol hydrochloride:

(-)-Isoproterenol hydrochloride Related Antibodies

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Description

(-)-Isoproterenol (Levisoprenaline; Proternol L) hydrochloride is a β-adrenoceptor agonist. (-)-Isoproterenol induces ventricular remodeling[1].

In Vivo

(-)-Isoproterenol hydrochloride (85 mg/kg; s.c.; daily for two consecutive days) induces ventricular remodeling (VR) in rat[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 180-200 g, 6-7 weeks, Healthy male Sprague Dawley rats[1]
Dosage: 85 mg/kg
Administration: S.c.; daily for two consecutive days
Result: Decreased the systolic blood pressure (SBP) levels, increased LV weight index (LVWI) and heart weight index (HWI), the average cross section area markedly increased, significant increased in the levels of NT-proBNP in the myocardium.
Molecular Weight

247.72

Formula

C11H18ClNO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC=C([C@@H](O)CNC(C)C)C=C1O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (504.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0368 mL 20.1841 mL 40.3682 mL
5 mM 0.8074 mL 4.0368 mL 8.0736 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0368 mL 20.1841 mL 40.3682 mL 100.9204 mL
5 mM 0.8074 mL 4.0368 mL 8.0736 mL 20.1841 mL
10 mM 0.4037 mL 2.0184 mL 4.0368 mL 10.0920 mL
15 mM 0.2691 mL 1.3456 mL 2.6912 mL 6.7280 mL
20 mM 0.2018 mL 1.0092 mL 2.0184 mL 5.0460 mL
25 mM 0.1615 mL 0.8074 mL 1.6147 mL 4.0368 mL
30 mM 0.1346 mL 0.6728 mL 1.3456 mL 3.3640 mL
40 mM 0.1009 mL 0.5046 mL 1.0092 mL 2.5230 mL
50 mM 0.0807 mL 0.4037 mL 0.8074 mL 2.0184 mL
60 mM 0.0673 mL 0.3364 mL 0.6728 mL 1.6820 mL
80 mM 0.0505 mL 0.2523 mL 0.5046 mL 1.2615 mL
100 mM 0.0404 mL 0.2018 mL 0.4037 mL 1.0092 mL
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(-)-Isoproterenol hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-Isoproterenol5984-95-2LevisoprenalineProternol LAdrenergic ReceptorBeta Receptorventricular remodelingLVWIHWIInhibitorinhibitorinhibit

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