1. Immunology/Inflammation
  2. PGE synthase
  3. ML388

ML388 is a potent and selective hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with an IC50 of 34 nM. ML388 induces PGE2 production in A549 cells and LNCaP prostate cancer cells.

For research use only. We do not sell to patients.

ML388 Chemical Structure

ML388 Chemical Structure

CAS No. : 1537192-31-6

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Description

ML388 is a potent and selective hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with an IC50 of 34 nM. ML388 induces PGE2 production in A549 cells and LNCaP prostate cancer cells[1].

IC50 & Target

IC50: 34 nM (hydroxyprostaglandin dehydrogenase (HPGD))[1]

Molecular Weight

320.43

Formula

C20H24N4

CAS No.
SMILES

CC1=CC=C(C=C1)N2C(C)=C(C=C2C)C3=NN=C4N3CCCCC4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ML388
Cat. No.:
HY-120581
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