2. Anti-infection Cell Cycle/DNA Damage
  3. HIV CDK
  4. SMAPP1

SMAPP1 is an activator of protein phosphatase-1 (PP1). SMAPP1 increases phosphorylation of CDK9’s Ser90 and Thr186 residues, but not Ser175. SMAPP1 induces HIV-1 replication, upregulates HIV-1 transcription that led to the reactivation of latent HIV-1 provirus.

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SMAPP1 Chemical Structure

SMAPP1 Chemical Structure

CAS No. : 327081-00-5

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SMAPP1 Related Antibodies

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HIV HIV-1 HIV-2

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CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

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Description

SMAPP1 is an activator of protein phosphatase-1 (PP1). SMAPP1 increases phosphorylation of CDK9’s Ser90 and Thr186 residues, but not Ser175. SMAPP1 induces HIV-1 replication, upregulates HIV-1 transcription that led to the reactivation of latent HIV-1 provirus[1].

Molecular Weight

563.65

Formula

C27H25N5O5S2
CAS No.
SMILES

O=C(C1N(S(=O)(C2=CC=C(C)C=C2)=O)CC3=C(C=CC=C3)C1)NC4=CC=C(S(=O)(NC5=NC=CC=N5)=O)C=C4
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SMAPP1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SMAPP1327081-00-5SMAPP 1SMAPP-1HIVCDKHuman immunodeficiency virusCyclin dependent kinaseInhibitorinhibitorinhibit

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