MMC(TMZ)-TOC TFA

Cat. No.: HY-163317A: FAQs
Data Sheet Handling Instructions Technical Support

MMC(TMZ)-TOC TFA has high binding affinity and selectivity for somatostatin receptor subtype-2 (SSTR2). MMC(TMZ)-TOC TFA targets delivery of TMZ to SSTR2-positive tumor cells. MMC(TMZ)-TOC TFA can be used for the research of cancer.

For research use only. We do not sell to patients.

MMC(TMZ)-TOC TFA Chemical Structure

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of MMC(TMZ)-TOC TFA:

MMC(TMZ)-TOC TFA Get quote

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•Related Small Molecules:

•Related Proteins:

View All Somatostatin Receptor Isoform Specific Products:

View All Isoforms

SSTR1 SSTR2 SSTR3 SSTR5 SSTR4

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

1725.82

Formula

C₇₄H₉₉F₃N₂₀O₂₁S₂

SMILES

OC(CN1CCN(CC(N[C@H](CC2=CC=CC=C2)C(N[C@@H](CSSC[C@H](NC([C@@]([C@@H](C)O)([H])NC3=O)=O)C(N[C@@H]([C@@H](C)O)CO)=O)C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](C(N[C@H]3CCCCN)=O)CC5=CC6=C(N5)C=CC=C6)=O)=O)=O)=O)CCN(CC(O)=O)CCN(C(CCNC(C7=C(N8C=N7)N=NN(C)C8=O)=O)=O)CC1)=O.OC(C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (57.94 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.5794 mL	2.8972 mL	5.7943 mL
5 mM	0.1159 mL	0.5794 mL	1.1589 mL
10 mM	0.0579 mL	0.2897 mL	0.5794 mL

View the Complete Stock Solution Preparation Table

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. AghaAmiri S, et al. Somatostatin Receptor Subtype-2 Targeting System for Specific Delivery of Temozolomide. J Med Chem. 2024 Feb 22;67(4):2425-2437. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.5794 mL	2.8972 mL	5.7943 mL	14.4859 mL
	5 mM	0.1159 mL	0.5794 mL	1.1589 mL	2.8972 mL
	10 mM	0.0579 mL	0.2897 mL	0.5794 mL	1.4486 mL
	15 mM	0.0386 mL	0.1931 mL	0.3863 mL	0.9657 mL
	20 mM	0.0290 mL	0.1449 mL	0.2897 mL	0.7243 mL
	25 mM	0.0232 mL	0.1159 mL	0.2318 mL	0.5794 mL
	30 mM	0.0193 mL	0.0966 mL	0.1931 mL	0.4829 mL
	40 mM	0.0145 mL	0.0724 mL	0.1449 mL	0.3621 mL
	50 mM	0.0116 mL	0.0579 mL	0.1159 mL	0.2897 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

MMC(TMZ)-TOC TFA Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMC(TMZ)-TOCSomatostatin ReceptorSSTRsSSTRSSTR2cancerTMZInhibitorinhibitorinhibit

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