2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP-2 Inhibitor I

MMP-2 Inhibitor I (OA-Hy) is a potent MMP-2 inhibitor with a Ki of 1.7 μM.

For research use only. We do not sell to patients.

MMP-2 Inhibitor I Chemical Structure

MMP-2 Inhibitor I Chemical Structure

CAS No. : 10335-69-0

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1 mg USD 75 In-stock
5 mg USD 215 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

MMP-2 Inhibitor I Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

MMP-2 Inhibitor I (OA-Hy) is a potent MMP-2 inhibitor with a Ki of 1.7 μM[1].

IC50 & Target[2]

MMP-2

1.7 μM (Ki)

In Vitro

MMP-2 inhibitor I (OA-Hy; 5 μM; pretreated for 30 min) clearly suppresses R1881-enhanced LNCaP cell migration[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MMP-2 Inhibitor I Related Antibodies

Cell Invasion Assay[1]

Cell Line: LNCaP cells
Concentration: 5 μM
Incubation Time: Pretreated for 30 min and then co-incubated for 48 h
Result: R1881-enhanced LNCaP cell migration was clearly suppressed.
Molecular Weight

297.48

Formula

C18H35NO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ONC(CCCCCCC/C=C\CCCCCCCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (168.08 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3616 mL 16.8079 mL 33.6157 mL
5 mM 0.6723 mL 3.3616 mL 6.7231 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.23%

SDS (251 KB)

COA (238 KB) HNMR (1653 KB) RP-HPLC (247 KB) MS (255 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3616 mL 16.8079 mL 33.6157 mL 84.0393 mL
5 mM 0.6723 mL 3.3616 mL 6.7231 mL 16.8079 mL
10 mM 0.3362 mL 1.6808 mL 3.3616 mL 8.4039 mL
15 mM 0.2241 mL 1.1205 mL 2.2410 mL 5.6026 mL
20 mM 0.1681 mL 0.8404 mL 1.6808 mL 4.2020 mL
25 mM 0.1345 mL 0.6723 mL 1.3446 mL 3.3616 mL
30 mM 0.1121 mL 0.5603 mL 1.1205 mL 2.8013 mL
40 mM 0.0840 mL 0.4202 mL 0.8404 mL 2.1010 mL
50 mM 0.0672 mL 0.3362 mL 0.6723 mL 1.6808 mL
60 mM 0.0560 mL 0.2801 mL 0.5603 mL 1.4007 mL
80 mM 0.0420 mL 0.2101 mL 0.4202 mL 1.0505 mL
100 mM 0.0336 mL 0.1681 mL 0.3362 mL 0.8404 mL
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MMP-2 Inhibitor I Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMP-2 Inhibitor I10335-69-0MMPMatrix metalloproteinasesMMP-2 inhibitorcell migrationInhibitorinhibitorinhibit

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