MST Assay Service

Microscale Thermophoresis (MST) is a sensitive and innovative technique for studing molecular interactions in solution. It combines the principles of thermophoresis and fluorescence to provide quantitative data on binding affinities and thermodynamic properties in a highly versatile and label-free way.

How MST Works

The core principle of MST is the movement of particles in a temperature gradient. When a sample containing fluorescently labeled molecules is subjected to localized heating, the temperature difference causes these molecules to migrate toward cooler regions. The extent of this movement is influenced by the interactions between the labeled molecules and binding partners ,such as proteins or nucleic acids.

Applications

• Protein-Protein interaction analysis (including antigen-antibody, molecular chaperone-substrate, etc.)
• Protein-Peptide
  interaction analysis
• Protein-Small Molecule
  interaction analysis

• Peptide-Peptide
  interaction analysis
• Protein-Nucleic Acid
  interaction analysis
• Nucleic Acid Aptamer-Small Molecule
  interaction analysis

Key Features

• Low sample
  consumption
• Short measurement
  time
• Analysis in
  complex buffers
• No need for sample
  immobilization
• High sample
  compatibility

Quote for Service

MST Assay Service requires evaluation to determine the appropriate scheme and pricing For additional information about service price and technical specifics, please send an email to sales@MedChemExpress.com or contact the sales staff of MedChemExpress directly.