BLI Assay Service

Bio-Layer Interferometry (BLI) is a powerful label-free optical technique primarily used for studying biomolecular interactions in real-time. This method operates on the principle of optical interference, which occurs when light waves reflect off the bio-layer — a thin film consisting of biomolecules immobilized on the surface of a biosensor.

How BLI Works

In BLI, a biosensor probe coated with a bio-layer is immerse in a solution containing the target biomolecules. As these biomolecules bind to the bio-layer, changes in the thickness and refractive index of the layer take place, which in turn affects the interference pattern of reflected light. This results in a measurable shift in the wavelength of light that can be detected and quantified.

Applications

• Protein-Protein/Peptide/Antibody
  Interactions
• Protein-Nucleic Acid Interactions
• Protein-Lipid Interactions

• Protein-Small Molecule Interactions
• Virus and Vaccine Research
• Bacterial and CellularResearch

Key Features

• Label-free
  detection
• Low sample
  consumption with
  high sensitivity
• Real-Time
  Monitoring
• Wide range
  of applications
• High-throughput
  detection

Quote for Service

BLI Assay Service requires evaluation to determine the appropriate scheme and pricing For additional information about service price and technical specifics, please send an email to sales@MedChemExpress.com or contact the sales staff of MedChemExpress directly.