2. Metabolic Enzyme/Protease
  3. Oxidative Phosphorylation Mitochondrial Metabolism
  4. MS-L6

MS-L6 is a potent inhibitor of oxidative phosphorylation (OXPHOS) that can acts as electron transport chain complexes I (ETC-I) combining inhibition of NADH oxidation and uncoupling effect.

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MS-L6 Chemical Structure

MS-L6 Chemical Structure

CAS No. : 63498-32-8

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5 mg USD 95 In-stock
10 mg USD 150 In-stock
25 mg USD 300 In-stock
50 mg USD 480 In-stock
100 mg USD 760 In-stock
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Based on 1 publication(s) in Google Scholar

MS-L6 Related Antibodies

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Description

MS-L6 is a potent inhibitor of oxidative phosphorylation (OXPHOS) that can acts as electron transport chain complexes I (ETC-I) combining inhibition of NADH oxidation and uncoupling effect[1].

Molecular Weight

548.40

Formula

C20H28Br2N4S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N=C(NC1=CC=CC=C1)SCCCCCCSC(NC2=CC=CC=C2)=N.Br.Br
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (227.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8235 mL 9.1174 mL 18.2349 mL
5 mM 0.3647 mL 1.8235 mL 3.6470 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.95%

COA (244 KB) HNMR (266 KB) LCMS (95 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8235 mL 9.1174 mL 18.2349 mL 45.5872 mL
5 mM 0.3647 mL 1.8235 mL 3.6470 mL 9.1174 mL
10 mM 0.1823 mL 0.9117 mL 1.8235 mL 4.5587 mL
15 mM 0.1216 mL 0.6078 mL 1.2157 mL 3.0391 mL
20 mM 0.0912 mL 0.4559 mL 0.9117 mL 2.2794 mL
25 mM 0.0729 mL 0.3647 mL 0.7294 mL 1.8235 mL
30 mM 0.0608 mL 0.3039 mL 0.6078 mL 1.5196 mL
40 mM 0.0456 mL 0.2279 mL 0.4559 mL 1.1397 mL
50 mM 0.0365 mL 0.1823 mL 0.3647 mL 0.9117 mL
60 mM 0.0304 mL 0.1520 mL 0.3039 mL 0.7598 mL
80 mM 0.0228 mL 0.1140 mL 0.2279 mL 0.5698 mL
100 mM 0.0182 mL 0.0912 mL 0.1823 mL 0.4559 mL
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MS-L6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MS-L663498-32-8Oxidative PhosphorylationMitochondrial MetabolismATP/ADP ratiosSUDHL4 cellsSCID miceInhibitorinhibitorinhibit

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