2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. MSX-130

MSX-130 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis.

For research use only. We do not sell to patients.

MSX-130 Chemical Structure

MSX-130 Chemical Structure

CAS No. : 4051-59-6

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10 mg USD 139 In-stock
25 mg USD 292 In-stock
50 mg USD 468 In-stock
100 mg USD 750 In-stock
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Based on 1 publication(s) in Google Scholar

MSX-130 Related Antibodies

Top Publications Citing Use of Products

View All CXCR Isoform Specific Products:

View All Isoforms
CXCR CXCR1 CXCR2 CXCR3 CXCR4 CXCR7 CXCR6

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Description

MSX-130 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis[1].

IC50 & Target[1]

CXCR4

 

In Vitro

The C-X-C chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MSX-130 Related Antibodies
Molecular Weight

514.62

Formula

C36H26N4
CAS No.
Appearance

Solid

Color

Light yellow to green yellow

SMILES

C1(C2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2)=CC=C(C5=NC(C6=CC=CC=C6)=C(C7=CC=CC=C7)N5)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 2 mg/mL (3.89 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9432 mL 9.7159 mL 19.4318 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9432 mL 9.7159 mL 19.4318 mL 48.5795 mL
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MSX-130 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MSX-1304051-59-6MSX130MSX 130CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsCXCR4antagonistcancermetastasisInhibitorinhibitorinhibit

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HY-103010
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