2. Anti-infection
  3. Antibiotic Bacterial
  4. Mycaminosyltylonolide

Mycaminosyltylonolide is a potent antibiotic. Mycaminosyltylonolide shows antibacterial activity. Mycaminosyltylonolide inhibits luciferase synthesis.

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Mycaminosyltylonolide Chemical Structure

Mycaminosyltylonolide Chemical Structure

CAS No. : 61257-02-1

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Based on 1 publication(s) in Google Scholar

Mycaminosyltylonolide Related Antibodies

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Description

Mycaminosyltylonolide is a potent antibiotic. Mycaminosyltylonolide shows antibacterial activity. Mycaminosyltylonolide inhibits luciferase synthesis[1][2].

In Vitro

Mycaminosyltylonolid (3 µM) inhibits firefly luciferase mRNA translation in E. coli S30[1].
Mycaminosyltylonolid (0-128 µg/mL) shows antibacterial activity with MIC values of 1, 1, 2, 2, 1, 64 µg/mL for S. aureus FDA209Pa, S. aureus Smitha, S. aureus KUB857c, S. epidermidis KUB795g, E. faecalis ATCC29212h, K. pneumoniae NCTC9632h, respectively[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mycaminosyltylonolide Related Antibodies
Molecular Weight

597.74

Formula

C31H51NO10
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=CC[C@@H](C[C@H](C(/C=C/C(C)=C/[C@@H]([C@H](OC(C[C@H]([C@@H]1C)O)=O)CC)CO)=O)C)[C@@H]1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O)N(C)C)O
Structure Classification
Initial Source

Streptomyces fradiae,
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (167.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6730 mL 8.3648 mL 16.7297 mL
5 mM 0.3346 mL 1.6730 mL 3.3459 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6730 mL 8.3648 mL 16.7297 mL 41.8242 mL
5 mM 0.3346 mL 1.6730 mL 3.3459 mL 8.3648 mL
10 mM 0.1673 mL 0.8365 mL 1.6730 mL 4.1824 mL
15 mM 0.1115 mL 0.5577 mL 1.1153 mL 2.7883 mL
20 mM 0.0836 mL 0.4182 mL 0.8365 mL 2.0912 mL
25 mM 0.0669 mL 0.3346 mL 0.6692 mL 1.6730 mL
30 mM 0.0558 mL 0.2788 mL 0.5577 mL 1.3941 mL
40 mM 0.0418 mL 0.2091 mL 0.4182 mL 1.0456 mL
50 mM 0.0335 mL 0.1673 mL 0.3346 mL 0.8365 mL
60 mM 0.0279 mL 0.1394 mL 0.2788 mL 0.6971 mL
80 mM 0.0209 mL 0.1046 mL 0.2091 mL 0.5228 mL
100 mM 0.0167 mL 0.0836 mL 0.1673 mL 0.4182 mL
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Mycaminosyltylonolide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mycaminosyltylonolide61257-02-1AntibioticBacterialantibioticantibacterialfirefly luciferaseE. coliInhibitorinhibitorinhibit

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