2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. N-6-Methyl-2-deoxyadenosine

N-6-Methyl-2-deoxyadenosine 

Cat. No.: HY-W011725 Purity: ≥98.0%
COA Handling Instructions

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N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

N-6-Methyl-2-deoxyadenosine Chemical Structure

N-6-Methyl-2-deoxyadenosine Chemical Structure

CAS No. : 2002-35-9

Size Price Stock Quantity
5 mg USD 90 In-stock
10 mg USD 140 In-stock
25 mg USD 280 Get quote
50 mg USD 450 Get quote
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of N-6-Methyl-2-deoxyadenosine:

N-6-Methyl-2-deoxyadenosine Related Antibodies

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Description

N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

265.27

Formula

C11H15N5O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)C[C@H](N2C(N=CN=C3NC)=C3N=C2)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (376.97 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7697 mL 18.8487 mL 37.6974 mL
5 mM 0.7539 mL 3.7697 mL 7.5395 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (254 KB) HNMR (242 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7697 mL 18.8487 mL 37.6974 mL 94.2436 mL
5 mM 0.7539 mL 3.7697 mL 7.5395 mL 18.8487 mL
10 mM 0.3770 mL 1.8849 mL 3.7697 mL 9.4244 mL
15 mM 0.2513 mL 1.2566 mL 2.5132 mL 6.2829 mL
20 mM 0.1885 mL 0.9424 mL 1.8849 mL 4.7122 mL
25 mM 0.1508 mL 0.7539 mL 1.5079 mL 3.7697 mL
30 mM 0.1257 mL 0.6283 mL 1.2566 mL 3.1415 mL
40 mM 0.0942 mL 0.4712 mL 0.9424 mL 2.3561 mL
50 mM 0.0754 mL 0.3770 mL 0.7539 mL 1.8849 mL
60 mM 0.0628 mL 0.3141 mL 0.6283 mL 1.5707 mL
80 mM 0.0471 mL 0.2356 mL 0.4712 mL 1.1780 mL
100 mM 0.0377 mL 0.1885 mL 0.3770 mL 0.9424 mL
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N-6-Methyl-2-deoxyadenosine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-6-Methyl-2-deoxyadenosine2002-35-9Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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