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  4. N-Desmethylolanzapine

N-Desmethylolanzapine  (Synonyms: N-Demethylolanzapine; LY170055)

Cat. No.: HY-W009247 Purity: ≥98.0%
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N-Desmethylolanzapine is an antipsychotic drug. The formation of N-Desmethylolanzapine correlates with the level and activity of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine can be used in the study of antipsychotic drugs .

For research use only. We do not sell to patients.

N-Desmethylolanzapine Chemical Structure

N-Desmethylolanzapine Chemical Structure

CAS No. : 161696-76-0

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1 mg USD 125 In-stock
5 mg USD 290 In-stock
10 mg USD 436 Get quote
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of N-Desmethylolanzapine:

N-Desmethylolanzapine Related Antibodies

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Description

N-Desmethylolanzapine is an antipsychotic drug. The formation of N-Desmethylolanzapine correlates with the level and activity of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine can be used in the study of antipsychotic drugs [1].

Molecular Weight

298.41

Formula

C16H18N4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(S1)=CC2=C1NC3=CC=CC=C3N=C2N4CCNCC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 30 mg/mL (100.53 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3511 mL 16.7555 mL 33.5109 mL
5 mM 0.6702 mL 3.3511 mL 6.7022 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3511 mL 16.7555 mL 33.5109 mL 83.7774 mL
5 mM 0.6702 mL 3.3511 mL 6.7022 mL 16.7555 mL
10 mM 0.3351 mL 1.6755 mL 3.3511 mL 8.3777 mL
15 mM 0.2234 mL 1.1170 mL 2.2341 mL 5.5852 mL
20 mM 0.1676 mL 0.8378 mL 1.6755 mL 4.1889 mL
25 mM 0.1340 mL 0.6702 mL 1.3404 mL 3.3511 mL
30 mM 0.1117 mL 0.5585 mL 1.1170 mL 2.7926 mL
40 mM 0.0838 mL 0.4189 mL 0.8378 mL 2.0944 mL
50 mM 0.0670 mL 0.3351 mL 0.6702 mL 1.6755 mL
60 mM 0.0559 mL 0.2793 mL 0.5585 mL 1.3963 mL
80 mM 0.0419 mL 0.2094 mL 0.4189 mL 1.0472 mL
100 mM 0.0335 mL 0.1676 mL 0.3351 mL 0.8378 mL
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N-Desmethylolanzapine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Desmethylolanzapine161696-76-0N-Demethylolanzapine LY170055LY170055LY 170055LY-170055Othersantipsychotic agenthuman liver flavin-containing monooxygenaseInhibitorinhibitorinhibit

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