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N-dodecanoyl-L-Homoserine lactone  (Synonyms: C12-HSL)

Cat. No.: HY-118697 Purity: ≥98.0%
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N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.

For research use only. We do not sell to patients.

N-dodecanoyl-L-Homoserine lactone Chemical Structure

N-dodecanoyl-L-Homoserine lactone Chemical Structure

CAS No. : 137173-46-7

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
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Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid
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Based on 1 publication(s) in Google Scholar

N-dodecanoyl-L-Homoserine lactone Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE N-dodecanoyl-L-Homoserine lactone

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Description

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[1].

In Vitro

Disruption of cell-cell communication or quorum sensing (QS) is considered a stimulating approach for reducing bacterial pathogenicity and resistance[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

N-dodecanoyl-L-Homoserine lactone Related Antibodies
Molecular Weight

283.41

Formula

C16H29NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCC(N[C@H]1CCOC1=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (88.21 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5285 mL 17.6423 mL 35.2846 mL
5 mM 0.7057 mL 3.5285 mL 7.0569 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5285 mL 17.6423 mL 35.2846 mL 88.2114 mL
5 mM 0.7057 mL 3.5285 mL 7.0569 mL 17.6423 mL
10 mM 0.3528 mL 1.7642 mL 3.5285 mL 8.8211 mL
15 mM 0.2352 mL 1.1762 mL 2.3523 mL 5.8808 mL
20 mM 0.1764 mL 0.8821 mL 1.7642 mL 4.4106 mL
25 mM 0.1411 mL 0.7057 mL 1.4114 mL 3.5285 mL
30 mM 0.1176 mL 0.5881 mL 1.1762 mL 2.9404 mL
40 mM 0.0882 mL 0.4411 mL 0.8821 mL 2.2053 mL
50 mM 0.0706 mL 0.3528 mL 0.7057 mL 1.7642 mL
60 mM 0.0588 mL 0.2940 mL 0.5881 mL 1.4702 mL
80 mM 0.0441 mL 0.2205 mL 0.4411 mL 1.1026 mL
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N-dodecanoyl-L-Homoserine lactone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-dodecanoyl-L-Homoserine lactone137173-46-7C12-HSLOthersInhibitorinhibitorinhibit

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