2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. N-Propargyladenosine

N-Propargyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277). N-Propargyladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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N-Propargyladenosine Chemical Structure

N-Propargyladenosine Chemical Structure

CAS No. : 67005-97-4

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10 mg USD 160 In-stock
25 mg USD 320 In-stock
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Based on 1 publication(s) in Google Scholar

N-Propargyladenosine Related Antibodies

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Description

N-Propargyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. N-Propargyladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Molecular Weight

305.29

Formula

C13H15N5O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=CN=C3NCC#C)=C3N=C2)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (409.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2756 mL 16.3779 mL 32.7557 mL
5 mM 0.6551 mL 3.2756 mL 6.5511 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2756 mL 16.3779 mL 32.7557 mL 81.8893 mL
5 mM 0.6551 mL 3.2756 mL 6.5511 mL 16.3779 mL
10 mM 0.3276 mL 1.6378 mL 3.2756 mL 8.1889 mL
15 mM 0.2184 mL 1.0919 mL 2.1837 mL 5.4593 mL
20 mM 0.1638 mL 0.8189 mL 1.6378 mL 4.0945 mL
25 mM 0.1310 mL 0.6551 mL 1.3102 mL 3.2756 mL
30 mM 0.1092 mL 0.5459 mL 1.0919 mL 2.7296 mL
40 mM 0.0819 mL 0.4094 mL 0.8189 mL 2.0472 mL
50 mM 0.0655 mL 0.3276 mL 0.6551 mL 1.6378 mL
60 mM 0.0546 mL 0.2730 mL 0.5459 mL 1.3648 mL
80 mM 0.0409 mL 0.2047 mL 0.4094 mL 1.0236 mL
100 mM 0.0328 mL 0.1638 mL 0.3276 mL 0.8189 mL
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N-Propargyladenosine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Propargyladenosine67005-97-4Nucleoside Antimetabolite/Analogmuscle vasodilatorInhibitorinhibitorinhibit

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